| Sumario: | Significance & Background: Immediate identification and timely interventions are crucial for reducing morbidity and mortality in cancer patients diagnosed with sepsis. However, due to various challenges in the hospital, coordinating rapid sepsis care across various disciplines is a challenging task. Purpose: To advance frontline nurse-led quality improvement in sepsis care through timely recognition, rapid interventions, and coordinated efforts, ensuring safe, evidence-based treatment for cancer patients. Interventions: The sepsis program is grounded in quality improvement, fostering shared decision making, interdisciplinary collaboration, and open communication. The sepsis committee implemented a wide range of interventions, including physician and nursing champions, sepsis outlier reviews, and a sepsis coordinated response through overhead pages and text alerts. Bi-monthly Sepsis Pulse Check meetings enable case discussion led by frontline nursing staff. Before each meeting, nurses review all sepsis fallouts from the preceding week and share findings with nursing leadership, assigned physician reviewers, and pharmacists. Nurses present cases during meetings, fostering interdisciplinary collaboration for improvements. These meetings empower staff to recognize trends and develop action plans. Furthermore, all staff members involved in the fallouts, whether nurses or physicians, are promptly informed and provided with support through targeted improvement strategies aimed at optimizing outcomes and preventing future occurrences. This has enhanced sepsis management and aligned the department with national sepsis guidelines. Results: Enhancing nurses' roles in the cancer sepsis program has improved sepsis management. Our institution has consistently maintained the lowest sepsis mortality index among other comprehensive cancer centers. The department improved the door-to-antibiotic administration average time by 30%. The department also achieved 100% compliance from door-to-antibiotic time within one hour this fiscal year. Discussion: The sepsis Program highlights the value of frontline nurse-led quality improvement in emergency care, enabling early detection, timely interventions, and efficient team coordination. Ongoing reviews drive process enhancements and improve patient outcomes.
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