CYCLE 1 DAY 1 DEBRIEFS: IMPACT AND IMPLICATIONS FOR ONCOLOGY CLINICAL TRIALS.

Significance & Background: Clinical trial complexity in academic medical centers has increased over the past decade with new biomarkers, expanding data sources, changing regulatory guidelines, and pressure to make recruitment more efficient to lower costs. Multidisciplinary teams struggle to meet de...

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Publicado en:Oncology Nursing Forum Vol. 53; no. 2; p. 9
Autores principales: Agnew, Jennifer, Baroody, Christina, Tavernier, McKenzie, Thomas, Tiffany, Conley, Stefanie, Pogue, Meredith
Formato: Journal Article
Publicado: Oncology Nursing Society Mar2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2026
      vid: 53
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      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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          Agnew, Jennifer
          Baroody, Christina
          Tavernier, McKenzie
          Thomas, Tiffany
          Conley, Stefanie
          Pogue, Meredith
        affil: BSN RN OCN, UTSW Medical Center, Dallas, TX
      sug:
      ab: Significance & Background: Clinical trial complexity in academic medical centers has increased over the past decade with new biomarkers, expanding data sources, changing regulatory guidelines, and pressure to make recruitment more efficient to lower costs. Multidisciplinary teams struggle to meet demands in real time affecting patient experience and staff satisfaction. Purpose: Implement treatment start debriefs (Cycle 1 Day 1) to identify challenges and patient safety concerns as measured by the number and type of interventions administered and staff satisfaction with the C1D1 debriefs over a six-month period. Interventions: The workgroup created a checklist to facilitate C1D1 debrief discussions. They initiated C1D1 debriefing following the first treatment of patients enrolled in oncology clinical trials at a large academic medical institution. They engaged with members of the study team to reflect on the strengths and challenges faced during the treatment day. The team collected data on the number and types of interventions being performed in response to the challenges identified. They developed a paper survey to assess staff satisfaction and engagement with the implementation of C1D1 debriefs. Results: Since February 2025, preliminary feedback indicates that the multidisciplinary team feels more confident to manage the demands of Cycle 1 Day 1 after participating in a C1D1 debrief. Research and nursing leadership has endorsed the project and expressed interest in incorporating this practice for standard of care regimens. Formal data collection and outcome measurement are ongoing. Participants have also addressed that there is a need for electronic version of the survey to streamline the process. Sustained benefits will be measured by additional reassessment of team after next treatment. Discussion: Effective communication between clinical staff, pharmacy and clinical research is paramount as clinical trials become more complex to ensure patient safety and continuity of care. Debriefing is a way for the healthcare team to review and process an event that occurred in a learning non-judgmental setting. Establishing Cycle 1 Day 1 (C1D1) debriefs initiated immediately after treatment facilitates the collaboration of teams to discuss opportunities to improve the flow of the patient's visit, address threats to patient safety, and therefore improve staff satisfaction scores. Future steps include introducing the concept in the onboarding of new research staff or the initiation of a new study as well as explore it's implementation in standard of care regimens.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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