| Sumario: | Significance & Background: Patients receiving ambulatory infusion therapy often face logistical challenges when returning to the clinic for pump disconnection and port de-accessing, especially during inclement weather. Clinic closures and scheduling constraints can delay care, increase patient risk, and create bottlenecks in infusion center operations. Additionally, caregiver availability and transportation issues further complicate timely follow-up. These barriers prompted the need for a safe, patient-centered alternative. Purpose: This project aims to develop and implement a protocol allowing patients, with caregiver assistance, to safely disconnect medication pumps and de-access ports at home following treatment. The goal is to reduce delays in care, improve patient autonomy, and alleviate scheduling burdens during weather-related disruptions. Interventions: A multi- disciplinary team conducted a literature review and collaborated with local Waste Management services to ensure safe disposal of medical waste. The team developed: a de-accessing kit containing all necessary supplies; a one-page educational document outlining step-by-step instructions, signed by both patient and caregiver after a supervised return demonstration in the clinic; and an educational video for patients and caregivers to reference at home. Patients are selected based on clinical stability, caregiver availability, and ability to perform the procedure safely. Staff provide in-clinic training and verify competency before home implementation. Results: Data collection for this initiative is currently ongoing. Preliminary feedback from patients and caregivers has been positive, with early indications of improved convenience and reduced scheduling delays. As the project progresses, we are measuring: safety and success rate of at- home pump disconnection and port de-accessing; patient and caregiver satisfaction with the process and educational materials; impact on infusion center scheduling, particularly during inclement weather; and reduction in missed or delayed de-access appointments. These metrics will help evaluate the effectiveness, safety, and scalability of the intervention. Discussion: This intervention is expected to be both feasible and effective in enhancing continuity of care during weather-related disruptions and scheduling conflicts. Patients and caregivers are anticipated to demonstrate high levels of competency and satisfaction with the process. The project underscores the importance of flexible, patient-centered solutions in oncology nursing. Future steps include expanding eligibility criteria and exploring similar models for other ambulatory treatments.
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