ADVANCED PRACTICE PROVIDER INITIATED VITAMIN D PROTOCOL FOR ADULTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANT: QUALITY IMPROVEMENT PROJECT.
Significance & Background: Patients undergoing hematopoietic stem cell transplant (HSCT) have a high risk for vitamin D deficiency prior to and post trans-plantation as compared to the general population. The increasing prevalence in vitamin D deficiency among patients with HSCT may lead to post-tra...
| Publicado en: | Oncology Nursing Forum Vol. 53; no. 2; p. 134 |
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| Autor principal: | |
| Formato: | Journal Article |
| Publicado: |
Oncology Nursing Society
Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194211349&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194211349 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0190535X 4F0 jtl: Oncology Nursing Forum issn: 0190535X maglogo: N pubinfo: dt: Mar2026 vid: 53 iid: 2 pid: 12496 pub: Oncology Nursing Society place: Pittsburgh, Pennsylvania artinfo: ui: 194211349 10.1188/26.ONF.e26535271 194211349 ppf: 134 ppct: 0 formats: fmt: @attributes: type: P tig: atl: ADVANCED PRACTICE PROVIDER INITIATED VITAMIN D PROTOCOL FOR ADULTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANT: QUALITY IMPROVEMENT PROJECT. aug: au: Haraguni, Miki affil: DNP, UCLA Health, Los Angeles, CA sug: ab: Significance & Background: Patients undergoing hematopoietic stem cell transplant (HSCT) have a high risk for vitamin D deficiency prior to and post trans-plantation as compared to the general population. The increasing prevalence in vitamin D deficiency among patients with HSCT may lead to post-transplant com-plications, which significantly affect duration and quality of life among this population. Despite the importance of vitamin D, transplant Advanced Practice Provider (APP) underperform screening of vitamin D level and replacement therapy nationwide. Purpose: In this quality improvement (QI) project, the author aims at establishing the application of evidence based systematic vitamin D algorithm for transplant APP to provide consistent practice in vitamin D screening/replacement therapy for patients with HSCT. Interventions: The QI project utilizes observational cohort design at an APP-run outpatient HSCT clinic in an urban city of Southern California. The intervention includes an educational session regarding the importance of vitamin D supplementation and use of newly developed vitamin D algorithm for monitoring/supplementation. The effectiveness of intervention is evaluated by 1) the number of vitamin D serum test orders, and 2) the number/proportion of patients received vitamin D replacement therapy based on the algorithm at pre-transplant and 6 weeks post initial treatment. The author analyzes the data with a one-tailed t-test with a p-value of 0.05% (considered as statistically significant). Results: After the educational sessions, the compliance of ordering vitamin D serum leveled per national standards based on a new algorithm, and 50 % of patients initiated supple-mentation for levels below 30 ng/ml. At 6 weeks post initial implementation, the APP repeated the vitamin D serum level for 80% of patients. Discussion: Overall, this project was successful in showing the efficacy of an APP educational session as indicated by statistically significant improvements and clinically significance in the rate of screening and replacement therapy. Using a clear guideline based on vitamin D algorithm, APP holds potential to provide consistent high quality and cost effective care for this vulnerable population. Future rigorous studies, such as a randomized control trial to evaluate long term efficacy of vitamin D therapy, are recommended to strengthen the evidence of this practice and assist further dissemination. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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