| Sumario: | Background & aim: Infertility profoundly affects multiple aspects of human life, serving as a major stressor and often causing significant emotional distress for couples, especially women. This study investigated the relationship between the characteristics of infertility and symptoms of post-traumatic stress disorder (PTSD) in women undergoing fertility treatment. Methods: This cross-sectional study examined 473 infertile women who sought treatment at one Infertility Center, affiliated with Mashhad University of Medical Sciences, Mashhad, Iran from December 2020 to February 2022. Participants were selected through convenience sampling. Data collection involved completing a demographic and infertility-related characteristics questionnaire, the Fertility Problem Inventory (FPI), and the Post-traumatic Stress Disorder (PTSD) Checklist on a self-report basis. To analyse data, independent t-test, chi-square test, Pearson correlations, one-way ANOVA and multiple regression analyses using SPSS version 23 were employed. Results: Three Fertility Problem Inventory domains includingrejection of child-free lifestyle, social concern, and desire for parenthood showed a significant negative association with PTSD (p<.001). No significant relationship was found between PTSD and demographic factors or types of infertility. Conclusion: Considering negative association between PTSD and three Fertility Problem Inventory domains, screening for PTSD symptoms by healthcare providers could play a critical role in identifying, assessing, and treating traumarelated conditions in infertility care. So, further research is recommended to deepen our understanding of these relationships.
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