Inclusion of older adults in UK clinical research—the National Institute for Health and Care Research Year of Birth Project.
Introduction Inclusion of older adults in research ensures both equity and relevance. We used National Institute of Health and Care Research Year of Birth data to describe inclusion of older adults in contemporary UK clinical research. Methods We worked with English research networks to collect indi...
| Publicado en: | Age & Ageing Vol. 55; no. 5; pp. 1 - 9 |
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| Autores principales: | , , , , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
May2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=194264332&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 194264332 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: May2026 vid: 55 iid: 5 pid: 622 pub: Oxford University Press / USA artinfo: ui: 194264332 10.1093/ageing/afag143 ppf: 1 ppct: 8 formats: tig: atl: Inclusion of older adults in UK clinical research—the National Institute for Health and Care Research Year of Birth Project. aug: au: Patel, Martyn Tiwari, Divya Anwar, Shamaila Evans, Philip Meersschaert, Chloe Minhas, Jatinder S Masoli, Jane A H Quinn, Terence J affil: Norfolk and Norwich University Hospitals NHS Foundation Trust, Older Peoples Medicine, 7 Colney Lane, Norwich NR4 7UY, UK University Hospitals Dorset NHS Foundation Trust, Poole, Bournemouth, Christchurch, UK NIHR—RDN Coordinating Centre, Leeds, UK University of Exeter, Medical School (Primary Care), Exeter, UK Universite de Poitiers, Faculte de Sciences, Poitiers, Nouvelle-Aquitaine, France University of Leicester, Division of Cardiovascular Sciences, Leicester, UK University of Exeter, Epidemiology and Public Health, University of Exeter Medical School, College House, University of Exeter Medical School, St Luke's Campus Heavitree Road, Exeter EX4 4QJ, UKRoyal Devon and Exeter NHS Foundation Trust, Healthcare for Older Adults, Barrack Road, Exeter EX2 5DW, UK University of Glasgow, Cardiovascular and Medical Sciences, Glasgow Royal Infirmary, Walton Building, Glasgow G4 0SF, UK su: United Kingdom Medical specialties & specialists Palliative treatment Human research subjects Age distribution Population geography Patient selection Data management Clinical medicine research Descriptive statistics Heart failure Parkinson's disease Endowment of research Comparative studies Data analysis software Nosology sug: subj: Medical specialties & specialists Palliative treatment Human research subjects Age distribution Population geography United Kingdom Other Grantmaking and Giving Services Patient selection Data management Clinical medicine research Descriptive statistics Heart failure Parkinson's disease Endowment of research Comparative studies Data analysis software Nosology ab: Introduction Inclusion of older adults in research ensures both equity and relevance. We used National Institute of Health and Care Research Year of Birth data to describe inclusion of older adults in contemporary UK clinical research. Methods We worked with English research networks to collect individual participant level data on recruits into National Institute of Health and Care Research portfolio studies. We used data from 2022–2023 to 2023–2024 to assess participation. We described data in terms of geography, primary speciality managing the study and study characteristics. In subgroup analyses, we assessed inclusion of the 'oldest old' (aged over 85 years) and inclusion in research from three exemplars: heart failure, Parkinson's disease and palliative care. Results In total, 455 734 participants were included in the analyses. The most common age group included in UK research was 65–74 years (15.5%). People aged over 85 years were 3.2% of all recruits, and this proportion decreased over time. There was modest geographical variation in participant age but marked variation by recruiting speciality. People aged over 85 years accounted for less than 5% of the total participants recruited in 9 of 14 specialities assessed. Older adults were less likely to be recruited into commercial studies. For three conditions of interest, recruitment did not match population epidemiology. Conclusion This project has demonstrated feasibility of collecting participant age data at scale and provides important metrics for understanding study participation. While there is scope to improve older adult participation across all the study portfolio, there are major equity issues around inclusion in certain speciality areas and commercial research. To complement this abstract, a video abstract is available online. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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