Adverse Childhood Experiences and Anorexia Nervosa: Mediating Mechanisms and Risk by Adversity Patterns.
Objective: The current study aimed to investigate the mediating mechanisms linking adverse childhood experiences (ACEs) to anorexia nervosa (AN) and to examine whether distinct patterns of ACE exposure are associated with differential risks and mediation pathways. Method: Data for 9746 female indivi...
| Publicado en: | European Eating Disorders Review Vol. 34; no. 4; pp. 1140 - 1150 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194295542&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194295542 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10724133 BVM jtl: European Eating Disorders Review issn: 10724133 maglogo: Y pubinfo: dt: Jul2026 vid: 34 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 194295542 192299999 194295542 194295542 10.1002/erv.70101 194295542 ppf: 1140 ppct: 10 formats: tig: atl: Adverse Childhood Experiences and Anorexia Nervosa: Mediating Mechanisms and Risk by Adversity Patterns. aug: au: Sakurai, Haruka Ishikawa, Shuhei Okubo, Ryo Mitsui, Nobuyuki Miyano, Fumiya Kako, Yuki Takanobu, Keisuke Fujii, Yutaka Asakura, Satoshi Umegaki, Yusuke Chen, Chong Sasaki, Yohei Kato, Takahiro A. Tabuchi, Takahiro affil: Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo Hokkaido,, Japan sug: subj: Adverse Childhood Experiences Psychosocial Factors Anorexia Nervosa Risk Factors Risk Assessment Human Male Female Adolescence Adult Middle Age Aged Aged, 80 and Over Japan Cross Sectional Studies Prospective Studies Mediation Analysis Structural Equation Modeling Loneliness Social Networks Psychological Distress Rumination (Cognition) Personality Quality of Life Regression Models, Theoretical Confidence Intervals Causal Modeling Data Analysis Software Descriptive Statistics Funding Source Questionnaires Scales Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objective: The current study aimed to investigate the mediating mechanisms linking adverse childhood experiences (ACEs) to anorexia nervosa (AN) and to examine whether distinct patterns of ACE exposure are associated with differential risks and mediation pathways. Method: Data for 9746 female individuals were collected from nationally representative Japanese surveys. ACEs were assessed using a 15‐item Japanese ACE questionnaire, and AN was identified via self‐reported physician diagnosis. Causal mediation analysis and structural equation modelling were used to examine indirect pathways, while latent class analysis (LCA) was used to identify ACE patterns. Results: Greater ACE exposure was significantly associated with a higher AN prevalence. In mediation analyses, loneliness, psychological distress, and brooding rumination were the most influential mediators, forming a latent "negative affectivity" factor that significantly mediated ACEs and AN. The LCA identified four ACE profiles: "low adversities", "psychological abuse", "poverty", and "multiple adversities". Relative to the "low adversities" group, other classes showed higher AN prevalence, although class differences in prevalence and mediators were modest. Discussion: We demonstrated that the number of ACEs, rather than their patterns, increases AN risk. Negative affectivity was a consistent strong mediator across ACE patterns; thus, it can be an important target for intervention in trauma‐exposed individuals with AN. Highlights: Childhood trauma is a known risk factor for AN. However, the pathways and ways in which risk differs according to adversity patterns remain unclear.We found that "negative affectivity" (loneliness, psychological distress, brooding rumination) strongly mediated childhood trauma and anorexia nervosa, with risk related more to the number of adversities than to their type and minimal differences in mediators across trauma profiles.Targeting negative affectivity may support prevention and treatment in trauma‐affected individuals. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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