Hallucinogen Use and Associated Illicit Drug Use and Prescription Drug Misuse Among Adults in the USA: Results from a National Survey.

There has been increasing discussion regarding the legalization of hallucinogens in recent years. However, literature remains limited on the associations of hallucinogen use with prescription drug misuse and illicit drug use. This study aimed to address this knowledge gap by analyzing data from the...

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Publicado en:International Journal of Mental Health & Addiction Vol. 24; no. 3; pp. 2298 - 2316
Autores principales: Lee, Yen-Han, Arndt, Stephan, Joji, Christopher, Fleischer, Hannah, Shelley, Mack, Liu, Ching-Ti, Chang, Yen-Chang
Formato: Artículo
Publicado: Springer Nature Jun2026
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
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        atl: Hallucinogen Use and Associated Illicit Drug Use and Prescription Drug Misuse Among Adults in the USA: Results from a National Survey.
      aug:
        au:
          Lee, Yen-Han
          Arndt, Stephan
          Joji, Christopher
          Fleischer, Hannah
          Shelley, Mack
          Liu, Ching-Ti
          Chang, Yen-Chang
        affil:
          https://ror.org/036nfer12 University of Central Florida, 32816, Orlando, FL, USA
          https://ror.org/036jqmy94 University of Iowa, 52242, Iowa City, IA, USA
          https://ror.org/04rswrd78 Iowa State University, 50011, Ames, IA, USA
          https://ror.org/05qwgg493 Boston University, 02118, Boston, MA, USA
          https://ror.org/00zdnkx70 National Tsing Hua University, 30013, Hsinchu City, Taiwan
      su:
        Hallucinogenic drugs
        Medication abuse
        Drug legalization
        Substance abuse risk factors
        Drug abuse
        Health surveys
        Logistic regression analysis
      sug:
        subj:
          Hallucinogenic drugs
          Medication abuse
          Drug legalization
          Substance abuse risk factors
          Drug abuse
          Health surveys
          Logistic regression analysis
      keyword:
        Hallucinogen use
        Illicit drug use
        Medical and Health Sciences Public Health and Health Services
        Prescription drug misuse
        Hallucinogen use
        Illicit drug use
        Medical and Health Sciences Public Health and Health Services
        Prescription drug misuse
      ab: There has been increasing discussion regarding the legalization of hallucinogens in recent years. However, literature remains limited on the associations of hallucinogen use with prescription drug misuse and illicit drug use. This study aimed to address this knowledge gap by analyzing data from the 2021–2022 National Survey on Drug Use and Health, focusing on adults aged 18 years and older (unweighted n = 90,503). The primary independent variable was hallucinogen use status (never, lifetime, or past 12 months), and the outcomes included prescription drug misuse (pain relievers, tranquilizers, or stimulants) and illicit drug use (cocaine, crack, inhalants, heroin, or methamphetamine). A series of logistic regression models were conducted. In the final sample, 14.77% of respondents reported lifetime hallucinogen use, and 4.11% reported past 12-month use. Additionally, 10.99% reported prescription drug misuse, and 3.66% reported illicit drug use in the past 12 months. Regression analysis showed that, compared to those who had never used hallucinogens, participants reporting use in the past 12 months had significantly higher odds of prescription drug misuse (AOR = 1.43, 99% CI: 1.36, 1.50) and illicit drug use (AOR = 1.64, 99% CI: 1.57, 1.72) in the past 12 months. Given that recent hallucinogen use was associated with significantly higher odds of both prescription drug misuse and illicit drug use, policymakers and public health practitioners should consider hallucinogen use, particularly past-year use, as a potential indicator of broader substance misuse risks.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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