Association of Depression with Cardiac Autonomic Function and Food Addiction in Individuals in Psychopharmacological Treatment.

Major depressive disorder is a multifactorial condition and may be associated with food addiction and changes in cardiac autonomic dysfunction. This study investigated the occurrence of food addiction and cardiac autonomic function among individuals with depression and undergoing psychopharmacologic...

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Publicado en:International Journal of Mental Health & Addiction Vol. 24; no. 3; pp. 2684 - 2698
Autores principales: Bezerra, Tainá Patrícia Teixeira, da Costa, Paulo César Trindade, Martins, Vinicius José Baccin, Minervino, Alfredo José, de Brito Alves, José Luiz
Formato: Artículo
Publicado: Springer Nature Jun2026
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
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        atl: Association of Depression with Cardiac Autonomic Function and Food Addiction in Individuals in Psychopharmacological Treatment.
      aug:
        au:
          Bezerra, Tainá Patrícia Teixeira
          da Costa, Paulo César Trindade
          Martins, Vinicius José Baccin
          Minervino, Alfredo José
          de Brito Alves, José Luiz
        affil:
          https://ror.org/00p9vpz11 Department of Nutrition, Health Sciences Center, Federal University of Paraiba, Department of Nutrition Campus I – Jd. Cidade Universitária, 58051-900, João Pessoa, Paraiba, Brazil
          https://ror.org/00p9vpz11 Department of Physiology and Pathology, Health Sciences Center, Federal University of Paraiba, João Pessoa, Paraiba, Brazil
          https://ror.org/00p9vpz11 Department of Psychiatry, Medical Sciences Center, Federal University of Paraiba, João Pessoa, Paraiba, Brazil
      su:
        Mental depression
        Compulsive eating
        Heart beat
        Vagal tone
        Body mass index
        Frequency spectra
        Psychopharmacology
      sug:
        subj:
          Mental depression
          Compulsive eating
          Pharmaceutical and medicine manufacturing
          Heart beat
          Vagal tone
          Body mass index
          Frequency spectra
          Psychopharmacology
      keyword:
        Depression
        Food addiction
        Heart rate variability
        Psychopharmacological treatment
        Depression
        Food addiction
        Heart rate variability
        Psychopharmacological treatment
      ab: Major depressive disorder is a multifactorial condition and may be associated with food addiction and changes in cardiac autonomic dysfunction. This study investigated the occurrence of food addiction and cardiac autonomic function among individuals with depression and undergoing psychopharmacological treatment. The group depression (D) exhibited a higher body mass index (BMI) [mean 29.4 (5.7) vs. 26.4 (3.3); p = 0.022] and greater number of food addiction symptoms [3 (0–9) vs. 1.5 (0–9); p = 0.005] compared to the group control (C). Group D had lower LF (Low-Frequency band) (46.8 ± 21.0 vs. 61.1 ± 21.9), LF/HF ratio [0.78 (0.17–6.89) vs. 1.77 (0.15–6.67)], SD2/SD1 ratio (1.66 ± 0.67 vs. 2.05 ± 0.70), and DFA1 (0.90 ± 0.35 vs. 1.15 ± 0.25), but higher HF (High-Frequency band) (52.9 ± 20.9 vs. 34.9 ± 19.4). Furthermore, LF/HF ratio was positively correlated with depression severity (p = 0.002; Spearman's rho = 0.558; effect size Fisher's z = 0.629). Regression models adjusted for potential confounders showed that depressive symptoms were positively associated with low-frequency (LF) components and food addiction symptoms and negatively associated with high-frequency (HF) components (p < 0.05). Patients with depression exhibited changes in BMI, addictive eating symptoms, and cardiometabolic parameters, with a greater prevalence of parasympathetic tone.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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