Next generation trial design for intensive care unit rehabilitation.
The last 20 years have seen an explosion of research devoted to understanding the feasibility, safety, implementation, and patient and system outcomes of physical rehabilitation for patients who are critically ill in the intensive care unit (ICU). Multiple systematic reviews and meta-analyses have s...
| Publicado en: | PTJ: Physical Therapy & Rehabilitation Journal Vol. 106; no. 5; pp. 1 - 9 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Oxford University Press / USA
May2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194431862&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194431862 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15386724 MZW0 jtl: PTJ: Physical Therapy & Rehabilitation Journal issn: 15386724 maglogo: N pubinfo: dt: May2026 vid: 106 iid: 5 pid: 622 pub: Oxford University Press / USA artinfo: ui: 194431862 10.1093/ptj/pzag036 194431862 ppf: 1 ppct: 8 formats: tig: atl: Next generation trial design for intensive care unit rehabilitation. aug: au: Nordon-Craft, Amy Ohtake, Patricia J Smith, James M Engel, Heidi J Lowman, John D Moss, Marc Pastva, Amy M affil: Physical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, CO 80045, United States sug: subj: Intensive Care Units Critical Illness Rehabilitation Quality of Life Rehabilitation Methods Physical Therapy Methods Patient Centered Care Survivors Psychosocial Factors Mental Health Recovery Study Design Implementation Science Program Evaluation Therapeutic Exercise Early Ambulation Activities of Daily Living Health Status Health Information Systems Electrical Equipment and Supplies Interprofessional Relations Health Care Delivery ab: The last 20 years have seen an explosion of research devoted to understanding the feasibility, safety, implementation, and patient and system outcomes of physical rehabilitation for patients who are critically ill in the intensive care unit (ICU). Multiple systematic reviews and meta-analyses have shown ICU physical rehabilitation to be feasible, safe, contribute to reduced ICU and hospital stays, reduce days on mechanical ventilation, and improve functional level outcomes at ICU and hospital discharge. These data demonstrate that ICU physical rehabilitation offers transformative potential for improving functional independence and quality of life in patients who are critically ill. However, significant barriers persist in translating evidence from randomized controlled trials into routine clinical practice. These barriers include patient heterogeneity, inconsistent intervention protocols and reporting, and systemic obstacles to implementation. This article provides perspective on these key challenges and proposes strategies for designing next-generation trials. Impact : Survivors of critical illness often face lasting physical, cognitive, and mental health challenges, and physical rehabilitation in the ICU can improve recovery. This article explores the importance of tailoring physical rehabilitation to individual needs and proposes new research methods to improve the design and outcomes of future ICU trials. By addressing challenges, the authors provide practical solutions to make ICU rehabilitation more accessible and effective. These insights aim to enhance recovery and quality of life for ICU survivors. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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