Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk.
Background: Early temperament has been shown to predict socioemotional outcomes, but its neural correlates are not yet fully understood. In the current study, we investigated the relationship between early temperament and neuronal network functional connectivity (FC), and how these factors contribut...
| Publicado en: | Journal of Child Psychology & Psychiatry Vol. 67; no. 7; pp. 1203 - 1218 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
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Wiley-Blackwell
Jul2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=194548814&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 194548814 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00219630 JYY jtl: Journal of Child Psychology & Psychiatry issn: 00219630 maglogo: Y pubinfo: dt: Jul2026 vid: 67 iid: 7 pid: 480 pub: Wiley-Blackwell artinfo: ui: 194548814 10.1111/jcpp.70095 ppf: 1203 ppct: 15 formats: tig: atl: Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk. aug: au: Xie, Wanze Wang, Yiyi Sacks, Dashiell D. Nelson, Charles A. Bosquet Enlow, Michelle affil: School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China IDG/McGovern Institute for Brain Research, Peking University, Beijing, China Department of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston MA,, USA Department of Psychology, University of Chicago, Chicago IL,, USA Department of Psychiatry, Harvard Medical School, Boston MA,, USA Division of Developmental Medicine, Boston Children's Hospital, Boston MA,, USA Department of Pediatrics, Harvard Medical School, Boston MA,, USA Harvard Graduate School of Education, Cambridge MA,, USA su: Risk factors of attention-deficit hyperactivity disorder Parents Adolescent development Temperament Task performance Affinity groups Affective disorders Self-control Internalizing behavior Behavior disorders in children Attention Child development Psychological disengagement Pathological psychology Child behavior Children Risk assessment Statistical correlation Emotion regulation Mathematical variables Functional connectivity Infant development Research funding T-test (Statistics) Electroencephalography Questionnaires Pilot projects Analysis of covariance Multivariate analysis Descriptive statistics Magnetic resonance imaging Longitudinal method Large-scale brain networks Research Child Behavior Checklist Confidence intervals Comparative studies Data analysis software Factor analysis Relaxation for health Eye movements Regression analysis sug: subj: Risk factors of attention-deficit hyperactivity disorder Parents Adolescent development Temperament Task performance Affinity groups Affective disorders Self-control Internalizing behavior Behavior disorders in children Attention Child development Psychological disengagement Pathological psychology Child behavior Children Diagnostic Imaging Centers Risk assessment Statistical correlation Emotion regulation Mathematical variables Functional connectivity Infant development Research funding T-test (Statistics) Electroencephalography Questionnaires Pilot projects Analysis of covariance Multivariate analysis Descriptive statistics Magnetic resonance imaging Longitudinal method Large-scale brain networks Research Child Behavior Checklist Confidence intervals Comparative studies Data analysis software Factor analysis Relaxation for health Eye movements Regression analysis keyword: developmental psychopathology electroencephalography internalizing disorder neural networks developmental psychopathology electroencephalography internalizing disorder neural networks ab: Background: Early temperament has been shown to predict socioemotional outcomes, but its neural correlates are not yet fully understood. In the current study, we investigated the relationship between early temperament and neuronal network functional connectivity (FC), and how these factors contribute to the risk of psychopathology. Methods: Using a longitudinal cohort followed from infancy to age 7 (N = 749 collected at infancy), we assessed temperament through two approaches: data‐driven profiles extracted from parent‐reported questionnaires collected from infancy to age 3 and lab‐based assessments of behavioral inhibition (BI) at age 3. Symptoms of psychopathology were measured at age 7 with the parent‐reported Child Behavior Checklist (CBCL). Resting‐state EEG data collected at ages 3, 5, and 7, along with source‐space connectivity methods, were used to examine FC within brain networks. Results: Children with an emotionally and behaviorally dysregulated (EBD) profile, an identified risk factor for psychopathology, exhibited reduced FC in the frontoparietal network compared to their emotionally and behaviorally regulated (EBR) peers. BI at age 3 was also negatively correlated with FC in the ventral attention network at age 3 and the frontoparietal network at age 7. Additionally, frontoparietal FC moderated the relationship between early temperament and later attention‐deficit symptoms: EBD children showed higher levels of attention problems than their EBR peers, but only when frontoparietal FC was low. Conclusions: These findings underscore the importance of network connectivity in understanding early temperament and its socioemotional outcomes. Specifically, they highlight the role of attention and control networks in the development of psychopathology, suggesting potential targets for early interventions aimed at at‐risk children. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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