Life events and their subjective appraisal by children and adolescents in clinical high-risk states of psychosis: a cross-sectional comparison with inpatients with non-psychotic disorders and community subjects.
While childhood trauma and neglect are generally found to be increased in clinical high-risk of psychosis (CHR-P), findings on life events (LEs) are so far inconclusive, with some indication of a stress sensitization effect in CHR-P, leading to generally higher stress appraisals of LEs, and a LE-red...
| Published in: | European Child & Adolescent Psychiatry Vol. 35; no. 5; pp. 1677 - 1688 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Springer Nature
May2026
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194611715&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194611715 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: May2026 vid: 35 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 194611715 191687322 194611715 194611715 10.1007/s00787-025-02949-6 194611715 ppf: 1677 ppct: 11 formats: tig: atl: Life events and their subjective appraisal by children and adolescents in clinical high-risk states of psychosis: a cross-sectional comparison with inpatients with non-psychotic disorders and community subjects. aug: au: Kullmann, Celina Michel, Chantal Walger, Petra Franscini, Maurizia Traber-Walker, Nina Schimmelmann, Benno G. Flückiger, Rahel Reissner, Volker Schultze-Lutter, Frauke affil: https://ror.org/024z2rq82 Department of Psychiatry and Psychotherapy, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Bergische Landstraße 2, 40629, Düsseldorf, Germany sug: subj: Psychotic Disorders Risk Factors Psychotic Disorders Risk Factors Adverse Childhood Experiences Psychosocial Factors Life Experiences Risk Assessment Human Switzerland Germany Male Female Child Adolescence Cross Sectional Studies Comparative Studies Inpatients Community Living Psychotic Disorders Symptoms Interpersonal Relations Stress, Psychological Support, Social Descriptive Statistics Data Analysis Software Chi Square Test Kruskal-Wallis Test Mann-Whitney U Test Spearman's Rank Correlation Coefficient Regression Scales Psychological Tests Interview Guides Child: 6-12 years Adolescent: 13-18 years Male Female ab: While childhood trauma and neglect are generally found to be increased in clinical high-risk of psychosis (CHR-P), findings on life events (LEs) are so far inconclusive, with some indication of a stress sensitization effect in CHR-P, leading to generally higher stress appraisals of LEs, and a LE-reducing effect of negative symptoms. Thus, we studied 50 LEs and their appraisals as assessed with the Munich Life Event Scale in CHR-P patients according to ultra-high risk and basic symptom criteria and age- and sex-matched clinical inpatient (ClinS) and healthy controls (GPS; each n = 112, age 8–17 yrs., 57.1% female). LEs, particularly those of interpersonal nature, were increased in CHR-P compared to GPS but not ClinS, and their number and presence was positively related to subjective negative symptoms. Furthermore, appraisals rarely and only unsystematically differed between groups but correlated significantly in most cases with a more negative appraisal being related to a higher stress appraisal. Thus, there was no indication of a significant stress sensitization effect in CHR-P. Rather, the increased number of LEs, in particular interpersonal ones, likely increases the overall load of stress in terms of a stress accumulation and decreases the size of the supportive social network as well as increases negative symptoms. Thus, early interventions in CHR-P should also include improving strategies to deal with LEs, particularly those of interpersonal nature, to improve resilience and reduce burden of non-normative LEs. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|