Are We Moving Toward Diagnostic Stewardship Or Laboratory Retrogress On Clostridioides difficile Testing?

The widespread adoption of PCR-based testing for Clostridioides difficile infection (CDI) has replaced enzyme immunoassays (EIA) in the U.S., increasing sensitivity and reported healthcare-onset CDI (HO-CDI) cases. However, concerns about overdiagnosis persist, as PCR may detect asymptomatic coloniz...

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Bibliographic Details

Published in:	Sage Open Pathology Vol. 19; pp. 1 - 9
Main Authors:	Navarathna, Dhammika H., Cornelius, Lisa, Lukey, Janell, Wiley, Linda K., San Juan, Ma Rowena, Bolin, Sara C.
Format:	research tables/charts Journal Article
Published:	Sage Publications Inc. 6/16/2026
Online Access:	View this record in EBSCOhost