Assessing the Impact of a Digital Patient Navigation Tool for Iron Deficiency Anemia in Pregnancy: A Hybrid Effectiveness-Implementation Trial.

Objective: Iron deficiency anemia (IDA) is associated with adverse maternal and neonatal outcomes. Patient navigation tools have improved treatment and surveillance completion among postpartum populations. Our study aimed to evaluate the impact of prospectively implementing a digital patient navigat...

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Publicado en:American Journal of Perinatology Vol. 43; no. 9; pp. 1148 - 1156
Autores principales: Kumar, Natasha R., Butt, Zoya, Calcei, Jonathan B., Forkpa, Markolline, Mumford, Sunni, Levine, Lisa D., Hamm, Rebecca F.
Formato: pictorial research tables/charts Journal Article
Publicado: Thieme Medical Publishing Inc. Jul2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2026
      vid: 43
      iid: 9
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      pub: Thieme Medical Publishing Inc.
      place: New York, New York
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        10.1055/a-2719-4992
        194646024
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        atl: Assessing the Impact of a Digital Patient Navigation Tool for Iron Deficiency Anemia in Pregnancy: A Hybrid Effectiveness-Implementation Trial.
      aug:
        au:
          Kumar, Natasha R.
          Butt, Zoya
          Calcei, Jonathan B.
          Forkpa, Markolline
          Mumford, Sunni
          Levine, Lisa D.
          Hamm, Rebecca F.
        affil: Department of Obstetrics and Gynecology, University of Pennsylvania Health Systems, Philadelphia, Pennsylvania, United States
      sug:
        subj:
          Digital Health Utilization
          Patient Navigation
          Anemia, Iron Deficiency Therapy
          Prenatal Care
          Outcomes (Health Care)
          Patient-Reported Outcomes
          New England
          Human
          Pregnancy
          Female
          Tertiary Health Care
          Academic Medical Centers
          Pilot Studies
          Clinical Trials
          Hemoglobins Blood
          Multiple Logistic Regression
          Multiple Linear Regression
          Models, Statistical
          Descriptive Statistics
          Relative Risk
          Confidence Intervals
          Implementation Science
          Health Services Research
          Comparative Studies
          Fisher's Exact Test
          T-Tests
          Data Analysis Software
          Hypertension Epidemiology
          Chronic Disease Epidemiology
          Prevalence
          Insurance, Health
          Bivariate Statistics
          Self Report
          DSM
          Questionnaires
          Scales
          Female
      ab: Objective: Iron deficiency anemia (IDA) is associated with adverse maternal and neonatal outcomes. Patient navigation tools have improved treatment and surveillance completion among postpartum populations. Our study aimed to evaluate the impact of prospectively implementing a digital patient navigation tool for IDA in prenatal care (PN-IDA). Study Design: This pilot type 1 hybrid effectiveness-implementation trial utilized a difference-in-differences (DiD) design to compare pre- and postimplementation outcomes at an intervention site to a control site. The trial was performed at a tertiary academic center in the northeastern United States between April 2023 and April 2024. Patients with third-trimester Hgb < 9.5 g/dL were institutionally eligible for IV iron (IVFe) and included in this analysis. Dual primary outcomes were completion of ≥ 1 IVFe infusion and perceived health competence (validated eight-item survey). Implementation outcomes assessed penetration and fidelity. Multivariable logistical and linear regression models controlling for differences in site characteristics over time used interaction terms to estimate DiD. Results: Three hundred and seventy-eight patients were included. While IVFe completion increased at both sites (66–84% at the intervention site vs. 78–83% at the control site), there was no statistically significant difference (DiD RR: 1.13, 95% CI: 0.91–1.38). Perceived health competence remained similar at both sites (median score: 3.3–3.3 at the intervention site vs. median score: 3.3–3.1 at the control site, DiD RR: 0.15, 95% CI: −0.08 to 0.38). PN-IDA had a high level of penetration (i.e., integration of practice within a service setting), but poor fidelity (i.e., degree to which an intervention is delivered as intended). Sixty-six percent of eligible patients enrolled, but only 24% accessed PN-IDA more than once. Conclusion: PN-IDA implementation increased IVFe completion by 18% at the intervention site, but our study was underpowered to assess this difference. Future work will refine PN-IDA to optimize fidelity. Key Points: Completion of > 1 infusion increased by 18% at the intervention versus 5% at the control site (95% CI: 0.91–1.38). Two-thirds of eligible patients enrolled in the tool. Only 24% of enrolled patients accessed the tool > 1 time.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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