Task-State EEG Reveals Fine Hand Motor Impairment in Acute Ischemic Stroke: A Multidimensional Analysis of Cortical Dynamics.
Purpose: To systematically characterize the cortical dynamics underlying fine hand motor impairment in patients with acute ischemic stroke (AIS) using a multidimensional task-state electroencephalography (EEG) analysis framework. Materials and Methods: Fifteen patients with AIS and sixteen age- and...
| Publicado en: | NeuroRehabilitation Vol. 58; no. 4; pp. 636 - 651 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194727285&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194727285 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: Jun2026 vid: 58 iid: 4 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 194727285 193357882 194727285 194727285 10.1177/10538135261441843 194727285 ppf: 636 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Task-State EEG Reveals Fine Hand Motor Impairment in Acute Ischemic Stroke: A Multidimensional Analysis of Cortical Dynamics. aug: au: Deng, Ke Zhao, Jie Liu, Yuqi Tian, Chune Lin, Xiaofei Wei, Xiaoqing Li, Rui Liu, Weiping affil: Postgraduate Office, Xi'an Medical University, Xi'an, China sug: subj: Ischemic Stroke Complications Ischemic Stroke Rehabilitation Electroencephalography Functional Connectivity Task Performance and Analysis Hand Physiology Motor Skills Evaluation Human Male Female Adult Middle Age Aged China Prospective Studies Comparative Studies Cross Sectional Studies Funding Source Hospitals, Public Spearman's Rank Correlation Coefficient Descriptive Statistics Data Analysis Software Muscle Strength Activities of Daily Living NIH Stroke Scale Scales Large-Scale Brain Networks Psychomotor Performance Neuronal Plasticity Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Purpose: To systematically characterize the cortical dynamics underlying fine hand motor impairment in patients with acute ischemic stroke (AIS) using a multidimensional task-state electroencephalography (EEG) analysis framework. Materials and Methods: Fifteen patients with AIS and sixteen age- and sex-matched healthy controls were enrolled. EEG signals were recorded while participants performed three standardized fine motor tasks, including fist clenching, index finger pointing, and thumb-finger opposition. Source localization, time-frequency analysis, and brain network topology analysis were jointly applied to extract multidimensional electrophysiological features. Correlation analyses were further conducted to examine the relationships between EEG-derived metrics and clinical measures, including muscle strength grading, National Institutes of Health Stroke Scale (NIHSS) scores, and Activities of Daily Living (ADL) scores. Results: Compared with healthy controls, patients with AIS showed abnormal spatiotemporal cortical dynamics during fine hand movements. These abnormalities included delayed movement-related potentials, a shift of alpha- and beta-band event-related desynchronization from contralateral dominance toward more bilateral and diffuse activation, and altered brain network organization characterized by reduced network efficiency and changes in nodal centrality. In addition, EEG-derived features were significantly associated with clinical measures. Specifically, several event-related desynchronization/event-related synchronization (ERD/ERS)-related amplitudes and small-world properties were significantly correlated with muscle strength grading, NIHSS scores, and ADL scores after false discovery rate correction. Conclusion: Multidimensional task-state EEG analysis can characterize cortical activation abnormalities and network reorganization associated with fine hand motor impairment in patients with AIS. The identified EEG-derived metrics may serve as objective markers for post-stroke motor function assessment and recovery monitoring, and may help support individualized rehabilitation evaluation and planning. pubtype: Academic Journal doctype: diagnostic images equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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