A Novel ConvNeXtV2–MIL Approach for Accurate and Efficient Classification of Microscopic Fungal Morphology.

Fungal infections, especially in people with weakened immune systems, are a significant global health burden. Accurate identification of fungal morphology from microscopic images is a critical step in guiding timely antifungal treatment decisions. However, manual morphological assessment remains hig...

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Publicado en:Journal of Imaging Informatics in Medicine pp. 1 - 12
Autores principales: Ari, Nuray, Erten, Mehmet, Kayali, Sümeyra, Özdemir, Esra Yüzgeç, Koç, Canan, Özyurt, Fatih
Formato: Journal Article
Publicado: Springer Nature Jun2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-026-02052-5
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        atl: A Novel ConvNeXtV2–MIL Approach for Accurate and Efficient Classification of Microscopic Fungal Morphology.
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          Ari, Nuray
          Erten, Mehmet
          Kayali, Sümeyra
          Özdemir, Esra Yüzgeç
          Koç, Canan
          Özyurt, Fatih
        affil: Department of Medical Microbiology, Faculty of Medicine, Firat University
      sug:
      ab: Fungal infections, especially in people with weakened immune systems, are a significant global health burden. Accurate identification of fungal morphology from microscopic images is a critical step in guiding timely antifungal treatment decisions. However, manual morphological assessment remains highly dependent on expert mycologists and is prone to inter-observer variability. In this study, we propose a hybrid deep learning framework that integrates the ConvNeXtV2-Base architecture with a Multi-Head Attention–based Multiple Instance Learning module for automated classification of microscopic fungal morphology images. The framework was evaluated on the open-access DeFungi dataset, consisting of 3696 microscopic images representing five clinically meaningful fungal morphology classes. In comparative experiments, classical vision transformer (ViT) models achieved 91.20% accuracy, while MIL-enhanced ViT models reached 93.99%. The proposed ConvNeXtV2-Base + MIL hybrid method outperformed all evaluated architectures, achieving 98.90% classification accuracy. These results establish a new benchmark for automated fungal morphology classification and highlight the potential of AI-assisted decision-support tools to aid expert mycologists in morphology-based assessment workflows.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Unknown
    language: English
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