Acute and Chronic Effects of High-Load Resistance Training With Blood Flow Restriction in Healthy Adults: A Systematic Review and Meta-Analysis.
Supplemental Digital Content Is Available in the Text. Mckee, JR, Raj, IS, Marston, KJ, De Marco, K, Beere, M, Galna, B, Peiffer, JJ, Nosaka, K, and Scott, BR. Acute and chronic effects of high-load resistance training with blood flow restriction in healthy adults: A systematic review and meta-analy...
| Publicado en: | Journal of Strength & Conditioning Research Vol. 40; no. 7; pp. 822 - 843 |
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| Autores principales: | , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jul2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194775034&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194775034 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10648011 JSC jtl: Journal of Strength & Conditioning Research issn: 10648011 maglogo: N pubinfo: dt: Jul2026 vid: 40 iid: 7 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 194775034 194775034 194775034 10.1519/JSC.0000000000005467 194775034 ppf: 822 ppct: 21 formats: tig: atl: Acute and Chronic Effects of High-Load Resistance Training With Blood Flow Restriction in Healthy Adults: A Systematic Review and Meta-Analysis. aug: au: Mckee, James R. Selva Raj, Isaac Marston, Kieran J. De Marco, Kristen Beere, Michael Galna, Brook Peiffer, Jeremiah J. Nosaka, Kazunori Scott, Brendan R. affil: Physical Activity, Sport and Exercise (PHASE) Research Group, School of Allied Health (Exercise Science), Murdoch University, Perth, Australia sug: subj: Resistance Training Methods Training Effect (Physiology) Blood Flow Restriction Training Muscle Hypertrophy (Physiology) Evaluation Weight Lifting Muscle Strength Evaluation Task Performance and Analysis Exercise Physiology Human Systematic Review Meta Analysis Male Female Adult PubMed Data Analysis Software Models, Statistical Maximum Likelihood Confidence Intervals Pretest-Posttest Design Publication Bias Narratives Transducers Biomechanics Evaluation Electromyography Evaluation Cardiovascular System Physiology Evaluation Lactic Acid Blood RNA, Messenger Metabolism Biopsy Neovascularization, Physiologic Physiology Funding Source Checklists Adult: 19-44 years Male Female ab: Supplemental Digital Content Is Available in the Text. Mckee, JR, Raj, IS, Marston, KJ, De Marco, K, Beere, M, Galna, B, Peiffer, JJ, Nosaka, K, and Scott, BR. Acute and chronic effects of high-load resistance training with blood flow restriction in healthy adults: A systematic review and meta-analysis. J Strength Cond Res 40(7): 822–842, 2026—Blood flow restriction (BFR) improves muscle strength and size gains after low-load resistance training, though findings are conflicting for BFR with higher loads (≥60% of maximal strength). This systematic review with meta-analysis investigated whether high-load resistance training with BFR (a) further improves muscle size and strength and (b) increases acute performance, physiologic, and perceptual responses, when compared with conventional high-load resistance training. Six databases were searched to identify studies examining high-load resistance training with BFR in healthy adults. Risk of bias was assessed using Joanna Briggs Institute appraisal tools. A multilevel meta-analysis using the inverse-variance weighted random effects model was conducted on muscle strength and size outcomes. Acute data were synthesized narratively. Eight chronic studies and 34 acute studies were included. Very-low certainty evidence indicates that high-load resistance training with BFR does not further improve muscle strength (g = 0.11 [95% confidence intervals −0.11 to 0.33]) or size (g = 0.08 [95% confidence intervals −0.18 to 0.34]) adaptations compared with conventional high-load resistance training. Acutely, high-load resistance exercise with BFR may increase concentric bar velocity without altering electromyography amplitude, cardiorespiratory, metabolic, and molecular responses. Findings regarding perceptual responses and the number of repetitions completed during high-load resistance exercise with BFR are conflicting. Current evidence suggests that adding BFR to high-load resistance training is not beneficial for enhancing muscle size and strength, likely because of comparable physiologic demands. However, the application of wide cuffs at high pressures may acutely increase concentric bar velocity that could be explored as a potential method for improving muscular power. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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