Retention and Structural Inequities in Clinical Research: Insights from a Breastfeeding Intervention Study.
Objective. To be effective and generalizable, research must include diverse populations representative of the intended beneficiaries. Among women with low income in the United States, 74.9% initiate breastfeeding, but only 47.5% continue to six months. This analysis examined how structural inequitie...
| Publicado en: | Journal of Health Care for the Poor & Underserved Vol. 37; no. 2; pp. 673 - 692 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | pictorial research Journal Article |
| Publicado: |
Johns Hopkins University Press
May2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194878396&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194878396 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10492089 JPU jtl: Journal of Health Care for the Poor & Underserved issn: 10492089 maglogo: N pubinfo: dt: May2026 vid: 37 iid: 2 pid: 226 pub: Johns Hopkins University Press place: Baltimore, Maryland artinfo: ui: 194878396 194878396 194878396 10.1353/hpu.2026.a992136 194878396 ppf: 673 ppct: 19 formats: tig: atl: Retention and Structural Inequities in Clinical Research: Insights from a Breastfeeding Intervention Study. aug: au: LaPlant, Helen Wie Cunningham, Shayna Guan, Zhe Franics-Edoziuno, Confidence Alhabodal, Ashwag Scott, Dana rie rshall-Crim, ry Freytes, Idelisa Henderson, Wendy Walsh, Stephen Lucas, Ruth sug: subj: Research, Medical Research Subject Retention Health Status Disparities Health Inequities Breast Feeding Promotion Program Evaluation Economic Factors Race Factors Ethnic Groups Human Female Adolescence Adult Secondary Analysis Prospective Studies Descriptive Statistics Data Analysis Software Interviews Algorithms Kaplan-Meier Estimator Survival Analysis Log-Rank Test Cox Proportional Hazards Model Multivariate Analysis Hispanic Americans Bivariate Statistics Income Socioeconomic Factors Age Factors Educational Status Adolescent: 13-18 years Adult: 19-44 years Female ab: Objective. To be effective and generalizable, research must include diverse populations representative of the intended beneficiaries. Among women with low income in the United States, 74.9% initiate breastfeeding, but only 47.5% continue to six months. This analysis examined how structural inequities, indicated by income, race, and ethnicity, affect participant retention in a breastfeeding intervention. Methods. Participants (N=250) enrolled in PROMPT, a longitudinal randomized text-based breastfeeding self-management intervention trial. Cox proportional hazards models were used to analyze retention over 24 weeks. Results. Overall retention was 72%. Dropout risk was significantly higher among Hispanic and non-Hispanic Black participants (HR 2.86, p<.001), and among those with lower income (HR 2.61, p<.001). A three-factor model (including income, race/ethnicity, and age) was statistically significant overall (p=.0001), though individual predictors were not. Conclusion. Structural inequities may contribute to differential retention in breastfeeding trials, highlighting the need for equity-focused recruitment and retention strategies. pubtype: Academic Journal doctype: pictorial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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