Effectiveness of Pre‐Pregnancy Weight Loss Interventions on the Risk of Gestational Diabetes Mellitus in Overweight or Obese Women: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials.
Objective: To synthesize randomized controlled trials (RCTs) regarding the effectiveness of pre‐pregnancy weight loss interventions on the risk of gestational diabetes mellitus (GDM) in women with overweight or obesity. Methods: Comprehensive literature searches were conducted across nine databases...
| Publicado en: | Worldviews on Evidence-Based Nursing (John Wiley & Sons, Inc.) Vol. 23; no. 3; pp. 1 - 11 |
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| Autores principales: | , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
John Wiley & Sons, Inc.
Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194919661&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194919661 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17416787 NRNX jtl: Worldviews on Evidence-Based Nursing (John Wiley & Sons, Inc.) issn: 17416787 maglogo: N pubinfo: dt: Jun2026 vid: 23 iid: 3 pid: 52269 pub: John Wiley & Sons, Inc. artinfo: ui: 194919661 194919661 194919661 10.1111/wvn.70128 194919661 ppf: 1 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Effectiveness of Pre‐Pregnancy Weight Loss Interventions on the Risk of Gestational Diabetes Mellitus in Overweight or Obese Women: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials. aug: au: Jiang, Yucheng Mao, Yilin Li, Li Wang, Na Zhu, Zheng Ding, Yan affil: Obstetrics and Gynaecology Hospital of Fudan University, Shanghai, China sug: subj: Prepregnancy Care Weight Reduction Programs Diabetes Mellitus, Gestational Risk Factors Diabetes Mellitus, Gestational Prevention and Control Obesity Therapy Treatment Outcomes Risk Assessment Obesity Complications Human Systematic Review Meta Analysis Pregnancy Female Body Weight Body Mass Index Confidence Intervals Odds Ratio Pregnancy Complications Checklists Descriptive Statistics Data Analysis Software Adult PubMed Medline Embase Cochrane Library CINAHL Database Adult: 19-44 years Female ab: Objective: To synthesize randomized controlled trials (RCTs) regarding the effectiveness of pre‐pregnancy weight loss interventions on the risk of gestational diabetes mellitus (GDM) in women with overweight or obesity. Methods: Comprehensive literature searches were conducted across nine databases from inception to May 2024. RCTs comparing pre‐pregnancy weight loss interventions with blank control or active control among adult women with overweight or obesity were included. Meta‐analyses, using a random‐effects model, were performed to pool results of RCTs. Results: Six studies, including 1632 participants, were included. The effectiveness of pre‐pregnancy weight loss interventions on changes in weight and body mass index (BMI) was statistically significant (mean difference [MD] = −6.02, 95% confidence interval [CI] [−8.94, −3.10], I2 = 98%; MD = −2.22, 95% CI [−3.44, −1.00], I2 = 98%). However, there was no statistically significant difference in the risk of GDM in women receiving pre‐pregnancy weight loss interventions compared with controls (Odd Ratio [OR] = 0.70, 95% CI [0.48, 1.03], I2 = 2%). Linking Evidence to Action: Pre‐pregnancy weight loss interventions do not significantly impact the risk of GDM in women with overweight or obesity. Due to the small number of studies, small sample size, and large heterogeneity of pre‐pregnancy weight loss interventions, further research is required. Trial Registration: ClinicalTrials.gov identifier: CRD42023482808 pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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