The impact of medication management interventions on healthcare utilisation in people with dementia: a systematic review with meta-analysis.

Background Medication management interventions are designed to reduce medication-related harms in older people with dementia; however, their effect on healthcare utilisation remains unclear. Objective To summarise the impact of medication management interventions on healthcare utilisation in people...

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Publicado en:Age & Ageing Vol. 55; no. 6; pp. 1 - 13
Autores principales: Yu, Jiefei, Gnjidic, Danijela, Nastatos, Xenia, Sawan, Mouna
Formato: Artículo
Publicado: Oxford University Press / USA Jun2026
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
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        10.1093/ageing/afag172
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        atl: The impact of medication management interventions on healthcare utilisation in people with dementia: a systematic review with meta-analysis.
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        au:
          Yu, Jiefei
          Gnjidic, Danijela
          Nastatos, Xenia
          Sawan, Mouna
        affil: The University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia
      su:
        Australia
        Taiwan
        United States
        Sweden
        Institutional care
        Hospital care
        Primary health care
        Evaluation of medical care
        Caregivers
        Professions
        Senile dementia
        Psychiatric drugs
        Education of physicians
        Medical care use
        Medical information storage & retrieval systems
        Statistical models
        Patient education
        Research funding
        CINAHL database
        Emergency room visits
        Meta-analysis
        Systematic reviews
        MEDLINE
        Odds ratio
        Medication therapy management
        Medical databases
        Confidence intervals
        Data analysis software
        Dementia patients
        Psychology information storage & retrieval systems
        Proportional hazards models
        Residential care
        Health care teams
      sug:
        subj:
          Institutional care
          Hospital care
          Primary health care
          Evaluation of medical care
          Caregivers
          Professions
          Senile dementia
          Psychiatric drugs
          Australia
          Taiwan
          United States
          Sweden
          Residential Mental Health and Substance Abuse Facilities
          Other Residential Care Facilities
          Offices of physicians
          Offices of Physicians (except Mental Health Specialists)
          Professional Organizations
          Education of physicians
          Medical care use
          Medical information storage & retrieval systems
          Statistical models
          Patient education
          Research funding
          CINAHL database
          Emergency room visits
          Meta-analysis
          Systematic reviews
          MEDLINE
          Odds ratio
          Medication therapy management
          Medical databases
          Confidence intervals
          Data analysis software
          Dementia patients
          Psychology information storage & retrieval systems
          Proportional hazards models
          Residential care
          Health care teams
      keyword:
        aged
        caregivers
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        dementia
        emergency room visits
        health care use
        healthcare utilisation
        https://dx.doi.org/10.1093/ageing/afag172
        inLanguage:en
        medication management
        older people
        publisher:Oxford University Press
        randomization
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42315167/
        systematic review
        aged
        caregivers
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        dementia
        emergency room visits
        health care use
        healthcare utilisation
        https://dx.doi.org/10.1093/ageing/afag172
        inLanguage:en
        medication management
        older people
        publisher:Oxford University Press
        randomization
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42315167/
        systematic review
      ab: Background Medication management interventions are designed to reduce medication-related harms in older people with dementia; however, their effect on healthcare utilisation remains unclear. Objective To summarise the impact of medication management interventions on healthcare utilisation in people with dementia. Data sources Embase, MEDLINE, Web of Science, Cochrane CENTRAL Register of Controlled Trials, CINAHL, PsycINFO. Study selection Interventional studies assessing the impact of medication management interventions on healthcare utilisation in people with dementia aged ≥65. Data extraction and synthesis Eligible randomised controlled trials (RCTs) were meta-analysed with risk ratios (RR), 95% confidence intervals (CIs) using a fixed-effect model. Outcomes from non-randomised studies were summarised through narrative synthesis. Main outcomes Healthcare utilisation, including hospitalisation, emergency department visits, primary care and residential aged care home admissions. Results Seven RCTs and five non-randomised studies were eligible for inclusion. Common interventions were physician education (n  = 5), physician and patient/carer education (n  = 2), physician targeted prescribing reminders (n  = 1) and multidisciplinary team-based interventions (n  = 5). Among these, physician and patient/carer targeted education resulted in a reduction in all-cause hospitalisation (RR =0.92, 95% CI [0.84–0.99], P  = .04) and emergency department visits (RR = 0.92, 95% CI [0.86–0.98], P  = .007) while multidisciplinary team-based interventions were effective in reducing drug-related hospital readmission (Hazard Ratio = 0.49, 95% CI [0.27–0.90], P  = .02). Conclusion This review found that physician and patient/carer targeted education showed the most promising effect on all-cause hospitalisation and emergency department visits. Future research should develop tailored educational interventions that address key aspects of medication management to optimise healthcare utilisation in people with dementia.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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