The association between the degree of frailty and the risk of hospital related adverse events in older acutely admitted patients.

Introduction Frailty is an age-related syndrome characterised by increased vulnerability. Hospital-related adverse events (AEs) are complications not directly caused by patient's conditions. While age has been widely studied, less is known about the effect of the degree of frailty on in-hospital AEs...

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Publicado en:Age & Ageing Vol. 55; no. 6; pp. 1 - 9
Autores principales: Alotaibi, Faris, Manktelow, Bradly, Alshibani, Abdullah, Linton, Adam, Banerjee, Jay
Formato: Artículo
Publicado: Oxford University Press / USA Jun2026
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Acceso en línea:Ver este registro en EBSCOhost
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          Alotaibi, Faris
          Manktelow, Bradly
          Alshibani, Abdullah
          Linton, Adam
          Banerjee, Jay
        affil:
          Imam Abdulrahman Bin Faisal University, College of Applied Medical Sciences, Emergency Medical Care Department. Dammam, Saudi ArabiaUniversity of Leicester, College of Life Sciences, School of Healthcare, Leicester, England, United Kingdom of Great Britain and Northern Ireland
          University of Leicester, College of Life Sciences, School of Healthcare, Leicester, England, United Kingdom of Great Britain and Northern Ireland
          King Saud bin Abdulaziz University for Health Sciences, College of Applied Medical Sciences, Emergency Medical Services Department, Riyadh, Saudi ArabiaUniversity of Leicester, College of Life Sciences, Health Sciences, Leicester, United Kingdom of Great Britain and Northern IrelandKing Abdullah International Medical Research Center, Riyadh, Saudi Arabia
          University Hospitals of Leicester NHS Trust, Department of Emergency and Specialist Medicine (ESM), Leicester, England, United Kingdom of Great Britain and Northern Ireland
          University Hospitals of Leicester NHS Trust, Department of Emergency and Specialist Medicine (ESM), Leicester, England, United Kingdom of Great Britain and Northern IrelandUniversity of Leicester, College of Life Sciences, Global Health, Lifestyle and Metabolic Health, Leicester, United Kingdom of Great Britain and Northern Ireland
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        United Kingdom
        Patients
        Drug side effects
        Hospital admission & discharge
        Retrospective studies
        Self-mutilation
        Hospital care of older people
        Disease risk factors
        Old age
        Risk assessment
        Poisson distribution
        Academic medical centers
        Research funding
        Frail elderly
        Scientific observation
        Discharge planning
        Descriptive statistics
        Medical records
        Acquisition of data
        Adverse health care events
        Length of stay in hospitals
        Confidence intervals
        Accidental falls
        Pressure ulcers
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          Patients
          Drug side effects
          Hospital admission & discharge
          Retrospective studies
          Self-mutilation
          Hospital care of older people
          Disease risk factors
          Old age
          United Kingdom
          Risk assessment
          Poisson distribution
          Academic medical centers
          Research funding
          Frail elderly
          Scientific observation
          Discharge planning
          Descriptive statistics
          Medical records
          Acquisition of data
          Adverse health care events
          Length of stay in hospitals
          Confidence intervals
          Accidental falls
          Pressure ulcers
      keyword:
        adverse event
        adverse events
        aged
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        Datix
        frail elderly
        frailty
        https://dx.doi.org/10.1093/ageing/afag175
        inLanguage:en
        older people
        patient safety
        publisher:Oxford University Press
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42315169/
        adverse event
        adverse events
        aged
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        Datix
        frail elderly
        frailty
        https://dx.doi.org/10.1093/ageing/afag175
        inLanguage:en
        older people
        patient safety
        publisher:Oxford University Press
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42315169/
      ab: Introduction Frailty is an age-related syndrome characterised by increased vulnerability. Hospital-related adverse events (AEs) are complications not directly caused by patient's conditions. While age has been widely studied, less is known about the effect of the degree of frailty on in-hospital AEs among older adults. Methods This single-centre observational study used routinely collected data from a university teaching hospital in the UK October 2017 and 2023. Patients aged ≥65 admitted via the Emergency d. Department (ED) with a recorded frailty score at ED using the Clinical Frailty Scale (CFS) were included. AE types were in-hospital falls, pressure ulcers, moisture damage, infections, medication-related events, self-harm, discharge/transfer incidents and hospital injuries. Poisson regression models were used to estimate associations between frailty and AEs, adjusting for age, sex, ethnicity, ED wait time and Inpatient (IP) length of stay. Results Out of 369 798 admissions, 158 470 were included, and the degree of frailty was significantly associated with increased risk of AE. Compared to non-frail patients, adjusted RRs for those with CFS 7–9: in-hospital falls (RR = 1.46), pressure ulcers (RR = 2.75), moisture damage (RR = 3.56), infections (RR = 2.03), discharge/transfer incidents (RR = 2.42) and hospital injuries (RR = 1.66). While AE risk increased with frailty, some AE showed a slight decline in the severely frail group. Conclusion The degree of frailty was associated with the risk of hospital-related AEs in older adults. Higher degree of frailty was associated with multiple AE types, supporting early frailty identification, targeted preventive strategies and tailored care for risk reduction.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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