| Summary: | The article focuses on the challenges and potential strategies for implementing medication review and deprescribing in older adults with polypharmacy, particularly in acute care settings. While medication review has proven effective in various healthcare environments, acute care presents barriers such as patient stress and clinical urgency that may limit its benefits, as shown in a recent randomized controlled trial. The authors suggest that adapting the timing, setting, and communication of medication reviews—such as involving geriatricians, family physicians, and dedicated staff in a calmer environment—could improve outcomes. They also highlight the importance of integrating deprescribing within comprehensive geriatric assessment frameworks and call for further research to identify optimal approaches and institutional settings for deprescribing in older populations.
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