Effects of a home-based exercise and physical activity intervention after inpatient rehabilitation on real-world mobility in older adults with cognitive impairment: a secondary analysis of a randomised controlled trial.

Background Persistent mobility limitations after inpatient rehabilitation are common in older adults with cognitive impairment (CI). Home-based exercise interventions can improve locomotor capacity during this vulnerable period; however, evidence that they improve real-world mobility is scarce. Obje...

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Publicado en:Age & Ageing Vol. 55; no. 6; pp. 1 - 11
Autores principales: Werner, Christian, Ullrich, Phoebe, Angeli, Letizia Degli, Trumpf, Rieke, Fleiner, Tim, Albites-Sanabria, Jose L, Palmerini, Luca, Abel, Bastian, Bongartz, Martin, Eckert, Tobias
Formato: Artículo
Publicado: Oxford University Press / USA Jun2026
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
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        10.1093/ageing/afag189
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        atl: Effects of a home-based exercise and physical activity intervention after inpatient rehabilitation on real-world mobility in older adults with cognitive impairment: a secondary analysis of a randomised controlled trial.
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          Werner, Christian
          Ullrich, Phoebe
          Angeli, Letizia Degli
          Trumpf, Rieke
          Fleiner, Tim
          Albites-Sanabria, Jose L
          Palmerini, Luca
          Abel, Bastian
          Bongartz, Martin
          Eckert, Tobias
        affil:
          Geriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany
          Geriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, GermanyDepartment of Medical Oncology, Thorax Clinic, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany
          Department of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" – DEI, University of Bologna, Bologna, Italy
          Department of Geriatric Psychiatry and Psychotherapy, LVR Hospital Cologne, Cologne, North Rhine-Westphalia, GermanyInstitute of Movement and Sport Gerontology, German Sport University Cologne, Cologne, North Rhine-Westphalia, Germany
          Institute for Geriatric Research, Ulm University Medical Centre, Ulm, Baden-Württemberg, GermanyAgaplesion Bethesda Clinic Ulm, Geriatric Centre Ulm, Ulm, Baden-Württemberg, GermanyInstitute of Medical Engineering and Mechatronics, Ulm University of Applied Sciences, Ulm, Baden-Württemberg, Germany
          Geriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, GermanyDepartment of Telemedicine and Remote Patient Monitoring, Robert Bosch Hospital, Stuttgart, Baden-Württemberg, Germany
      su:
        Elder care
        Community health services
        Evaluation of human services programs
        Health promotion
        Psychological tests
        Exercise physiology
        Rehabilitation nursing
        Research funding
        Secondary analysis
        Cognition disorders in old age
        Exercise therapy
        Questionnaires
        Descriptive statistics
        Geriatric Depression Scale
        Home rehabilitation
        Walking speed
        Confidence intervals
        Physical mobility
        Physical activity
      sug:
        subj:
          Elder care
          Community health services
          Evaluation of human services programs
          Health promotion
          Psychological tests
          Continuing Care Retirement Communities
          Residential Mental Health and Substance Abuse Facilities
          Other local, municipal and regional public administration
          All Other Outpatient Care Centers
          Community health centres
          Other Individual and Family Services
          Exercise physiology
          Rehabilitation nursing
          Research funding
          Secondary analysis
          Cognition disorders in old age
          Exercise therapy
          Questionnaires
          Descriptive statistics
          Geriatric Depression Scale
          Home rehabilitation
          Walking speed
          Confidence intervals
          Physical mobility
          Physical activity
      keyword:
        aged
        ageing
        beckwith-wiedemann syndrome
        cognitive dysfunction
        cognitive impairment
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        exercise
        https://dx.doi.org/10.1093/ageing/afag189
        inLanguage:en
        inpatients
        mobility
        motor activity
        older people
        physical activity
        publisher:Oxford University Press
        randomization
        rehabilitation
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42361312/
        secondary data analysis
        walking
        walking speed
        wearable electronic device
        williams syndrome
        aged
        ageing
        beckwith-wiedemann syndrome
        cognitive dysfunction
        cognitive impairment
        copyrightHolder:British Geriatrics Society
        copyrightYear:2026
        exercise
        https://dx.doi.org/10.1093/ageing/afag189
        inLanguage:en
        inpatients
        mobility
        motor activity
        older people
        physical activity
        publisher:Oxford University Press
        randomization
        rehabilitation
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42361312/
        secondary data analysis
        walking
        walking speed
        wearable electronic device
        williams syndrome
      ab: Background Persistent mobility limitations after inpatient rehabilitation are common in older adults with cognitive impairment (CI). Home-based exercise interventions can improve locomotor capacity during this vulnerable period; however, evidence that they improve real-world mobility is scarce. Objective To investigate the effects of a home-based exercise programme combined with physical activity (PA) promotion on real-world digital mobility outcomes (DMOs). Design Single-centre, double-blind, randomised, placebo-controlled trial. Setting Community. Participants 104 community-dwelling older adults with CI (82.3 ± 6.0 years; 75% women; Mini-Mental State Examination score 23.2 ± 2.4) recently discharged from inpatient geriatric rehabilitation. Methods The intervention group received a 12-week home-based exercise programme combined with behavioural change techniques to promote PA; the control group received a 12-week non-specific home-based placebo motor activity programme. DMOs related to walking amount, pattern and pace were measured over 48 h at baseline, post-intervention and after a 12-week follow-up using a single body-fixed sensor and validated processing algorithms. Results Post-intervention, small statistically significant improvements favouring the intervention group were observed in walking pattern and pace outcomes, including longer walking bout (WB) duration, higher walking speed and longer stride length in shorter (10–30 s) WBs, and higher 90 percentile walking speed in WBs >10 s. These improvements were not sustained at the 12-week follow-up. No between-group differences were found for walking amount. Conclusion The post-discharge home-based exercise programme combined with PA promotion showed small, short-term improvements in selected real-world walking pattern and pace outcomes in older adults with CI after inpatient rehabilitation; however, these effects were no longer evident at follow-up, and walking amount did not increase.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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