흉부 컴퓨터단층촬영에서 흔하게 발견되는 간질성 폐이상의 임상적 의의.
Purpose: This review summarizes the current definition, epidemiology, risk factors, and management strategies for interstitial lung abnormality (ILA). Current concepts: ILA is an incidental radiologic finding on chest computed tomography (CT) that suggests interstitial lung disease in individuals wi...
| Publicado en: | Journal of the Korean Medical Association / Taehan Uisa Hyophoe Chi Vol. 69; no. 6; pp. 441 - 448 |
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| Autor principal: | |
| Formato: | review tables/charts Journal Article |
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Korean Medical Association
Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195155938&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195155938 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19758456 B9M7 jtl: Journal of the Korean Medical Association / Taehan Uisa Hyophoe Chi issn: 19758456 maglogo: N pubinfo: dt: Jun2026 vid: 69 iid: 6 pid: 64891 pub: Korean Medical Association place: , <Blank> artinfo: ui: 195155938 195155938 195155938 10.5124/jkma.26.0033 195155938 ppf: 441 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: 흉부 컴퓨터단층촬영에서 흔하게 발견되는 간질성 폐이상의 임상적 의의. aug: au: Shin, Beomsu affil: Department of Allergy, Pulmonology and Critical Care Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea sug: subj: Lung Diseases, Interstitial Radiography Tomography, X-Ray Computed Radiography, Thoracic Lung Diseases, Interstitial Epidemiology Disease Progression Risk Factors Lung Diseases, Interstitial Therapy Age Factors Smoking Inhalation Exposure Genetic Risk Score Polymorphism, Single Nucleotide Mortality Risk Factors Lung Diseases, Interstitial Mortality Lung Diseases, Interstitial Physiopathology Lung Neoplasms Risk Factors Pulmonary Fibrosis Risk Factors Prevalence Lung Diseases, Interstitial Complications Respiratory Function Tests ab: Purpose: This review summarizes the current definition, epidemiology, risk factors, and management strategies for interstitial lung abnormality (ILA). Current concepts: ILA is an incidental radiologic finding on chest computed tomography (CT) that suggests interstitial lung disease in individuals without a prior clinical diagnosis. As defined by the Fleischner Society and recently updated by the American Thoracic Society, ILA is characterized by features such as ground-glass opacities, reticulation, lung distortion, traction bronchiectasis, honeycombing, or non-emphysematous cysts involving ≥5% of any lung zone. In addition, ILA is classified into non-subpleural, subpleural non-fibrotic, and subpleural fibrotic subtypes to facilitate assessment of progression risk. The prevalence of ILA ranges from 3% to 10% in the general population. Risk factors for ILA progression include advanced age, cigarette smoking, other inhalational exposures, and genetic susceptibility, particularly the MUC5B promoter polymorphism. Clinically, ILA is associated with increased all-cause and respiratory mortality, accelerated decline in lung function, and a higher risk of lung cancer and pulmonary fibrosis. Discussion and conclusion: ILA may represent an early or subclinical stage of pulmonary fibrosis. Therefore, standardized reporting and risk-based clinical management are essential. Patients with high-risk features, particularly those with the subpleural fibrotic subtype, require active monitoring with pulmonary function tests and longitudinal CT surveillance to mitigate adverse outcomes and enable timely intervention. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: Korean refInfo: holdings: @attributes: islocal: N |
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