Medication errors and therapy problems may drive antimicrobial resistance in Egypt.

Background: Antimicrobial resistance is a challenge in Egypt and the potential contributors are medication errors and drug therapy problems involving antimicrobial agents. Aim: To analyse, for corrective actions, antimicrobial-related drug therapy and management errors reported to the Egyptian Natio...

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Publicado en:Eastern Mediterranean Health Journal Vol. 32; no. 5; pp. 325 - 333
Autores principales: Abdulaziz, Hebatalla M., Yehya, Yasmein, Amin, Abdulrahman M., Diaa, Lamis, Eldeen, Shimaa Nasr, Elbehairy, Abeer, Emam, Shimaa S., Abdelgawad, Shereen M.
Formato: research tables/charts Journal Article
Publicado: World Health Organization mai2026
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Medication errors and therapy problems may drive antimicrobial resistance in Egypt.
      aug:
        au:
          Abdulaziz, Hebatalla M.
          Yehya, Yasmein
          Amin, Abdulrahman M.
          Diaa, Lamis
          Eldeen, Shimaa Nasr
          Elbehairy, Abeer
          Emam, Shimaa S.
          Abdelgawad, Shereen M.
        affil: Drug Utilization and Pharmacy Practice General Administration, Central Pharmaceutical Care Administration, Egyptian Drug Authority, Cairo, Egypt
      sug:
        subj:
          Drug Resistance, Microbial Egypt
          Antimicrobial Stewardship
          Medication Errors Evaluation
          Antiinfective Agents Therapeutic Use
          Egypt
          Human
          Retrospective Design
          Record Review
          Convenience Sample
          Descriptive Statistics
          Antibiotics, Combined Therapeutic Use
          Antiinfective Agents Administration and Dosage
          Prescriptions, Drug
          Medication Errors Prevention and Control
          Patient Safety
      ab: Background: Antimicrobial resistance is a challenge in Egypt and the potential contributors are medication errors and drug therapy problems involving antimicrobial agents. Aim: To analyse, for corrective actions, antimicrobial-related drug therapy and management errors reported to the Egyptian National Office for Handling and Reduction of Medication Errors. Methods: We analysed data on antimicrobial-related drug therapy and management error reported to the National Office for Handling and Reduction of Medication Errors by 46 hospitals in 2 Egyptian governorates between January 2020 and November 2024. Using descriptive statistics, and based on the WHO access, watch and reserve classification, we summarised the error types and antimicrobial agents involved. Results: Of the 162 638 valid error reports, 57 592 (35.4%) involved antimicrobials, of which 98.2% were combined drug therapy and management errors. The most common errors were related to prescription (96.7%), including dosing regimen (43.1%) and incorrect indication (33.8%). The most frequently implicated agents were ampicillin/sulbactam (12.0%), levofloxacin (11.5%), ceftriaxone (9.0%), and cefotaxime (7.2%). Watch group antibiotics accounted for 65.4% of the errors, followed by access (27.8%) and reserve (5.7%). Conclusion: Our findings provide important baseline data for strengthening antimicrobial stewardship in Egypt. Appropriate policies are needed to minimise antimicrobial-related errors, improve rational use of antimicrobials, strengthen antimicrobial surveillance, and mitigate the risk of inappropriate watch group prescriptions in Egypt.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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