Female participation in randomized controlled trials of motor rehabilitation after spinal cord injury: a systematic review.
Study design: Systematic Review Objectives: The objective of this study was to investigate female participation in spinal cord injury (SCI) motor rehabilitation randomized controlled trials (RCTs) which included the overall proportion of female participants and how this proportion changed with time...
| Publicado en: | Spinal Cord Vol. 64; no. 7; pp. 581 - 588 |
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| Autores principales: | , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Jul2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195184891&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195184891 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13624393 DZQ jtl: Spinal Cord issn: 13624393 maglogo: Y pubinfo: dt: Jul2026 vid: 64 iid: 7 pid: 2579 pub: Springer Nature place: Dordrecht, <Blank> artinfo: ui: 195184891 195184891 195184891 10.1038/s41393-026-01229-7 195184891 ppf: 581 ppct: 7 formats: tig: atl: Female participation in randomized controlled trials of motor rehabilitation after spinal cord injury: a systematic review. aug: au: Cameron, Lindsay Ryan, Sarah Bowman, Andrew Bateman, Emma A. Eng, Janice J. Mehta, Swati Sequeira, Keith Teasell, Robert affil: https://ror.org/02rkgge26 Lawson Research Institute at St. Joseph's Health Care London, London, Ontario, Canada sug: subj: Spinal Cord Injuries Rehabilitation Rehabilitation Methods Research Subjects Women Randomized Controlled Trials Motor Skills Human Systematic Review Descriptive Statistics Medline Embase Psycinfo CINAHL Database Data Analysis Software Female Checklists Linear Regression Kruskal-Wallis Test Post Hoc Analysis Chi Square Test Funding Source Female ab: Study design: Systematic Review Objectives: The objective of this study was to investigate female participation in spinal cord injury (SCI) motor rehabilitation randomized controlled trials (RCTs) which included the overall proportion of female participants and how this proportion changed with time post-injury (TPI), study quality and the intervention investigated. Methods: Systematic searches were conducted in MEDLINE, Embase, PsycInfo and CINAHL databases inclusive to December 31, 2024. Study eligibility included RCTs or RCT crossovers published in English and investigated an intervention for motor rehabilitation on adult participants with traumatic and/or non-traumatic SCI. Data from the RCTs was extracted and summarized using online Excel, with statistical analyses conducted in RStudio. Results: Overall, 252 RCTs met the inclusion criteria and were included in the dataset. Of these, 237 RCTs reported the sex of participants. The overall proportion of female participants was 22.4%, with no significant changes between 2000 and 2024. No significant differences were found between the proportion of female participants and TPI. High quality studies had significantly higher female participation compared to low quality studies (p = 0.008). Significantly higher female participation was found in RCTs investigating technology-based interventions (p < 0.001), with no significant differences found in pharmacological or non-technology-based interventions. Conclusions: The underrepresentation of female participants in studies of SCI motor rehabilitation limits the generalizability of research results and potentially hinders the availability of rehabilitation strategies for female individuals. Understanding what challenges may be preventing higher enrollment and implementing recruitment strategies may aid in increasing the number of female participants in SCI rehabilitation RCTs. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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