A New Choice for Doxycycline Prophylaxis.
The article focuses on the use of doxycycline prophylaxis to prevent sexually transmitted infections (STIs) such as syphilis, chlamydia, and gonorrhea, particularly among sexual and gender minorities disproportionately affected by these infections. Recent clinical trials and implementation studies d...
| Publicado en: | Clinical Infectious Diseases Vol. 82; no. 6; pp. 1063 - 1065 |
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| Autor principal: | |
| Formato: | commentary editorial Journal Article |
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Oxford University Press / USA
Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195186655&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195186655 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10584838 46X jtl: Clinical Infectious Diseases issn: 10584838 maglogo: N pubinfo: dt: Jun2026 vid: 82 iid: 6 pid: 622 pub: Oxford University Press / USA artinfo: ui: 195186655 195186655 195186655 10.1093/cid/ciaf044 195186655 ppf: 1063 ppct: 2 formats: tig: atl: A New Choice for Doxycycline Prophylaxis. aug: au: Klausner, Jeffrey D affil: Keck School of Medicine, University of Southern California, Los Angeles, California, USA sug: subj: Sexually Transmitted Diseases Prevention and Control HIV Infections Prevention and Control Anti-HIV Agents Therapeutic Use Pre-Exposure Prophylaxis Tenofovir Therapeutic Use Emtricitabine Therapeutic Use Doxycycline Men Who Have Sex With Men Trans Women Drug Combinations Outcomes (Health Care) Postexposure Follow-Up Drug Resistance, Microbial Patient Compliance Implementation Science ab: The article focuses on the use of doxycycline prophylaxis to prevent sexually transmitted infections (STIs) such as syphilis, chlamydia, and gonorrhea, particularly among sexual and gender minorities disproportionately affected by these infections. Recent clinical trials and implementation studies demonstrate that daily doxycycline or doxycycline taken within 72 hours post-exposure significantly reduces the incidence of Chlamydia trachomatis and Treponema pallidum infections, though it has limited impact on Neisseria gonorrhoeae due to existing antibiotic resistance. The study also highlights the feasibility and tolerability of combining doxycycline prophylaxis with HIV preexposure prophylaxis, with high adherence and minimal adverse effects reported. While concerns about emerging doxycycline-resistant Staphylococcus aureus exist, current evidence suggests that doxycycline prophylaxis may contribute to declining STI rates at the population level, underscoring the need for further research on antimicrobial resistance and implementation strategies. pubtype: Academic Journal doctype: commentary editorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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