Long-term trends in HIV-related stigma among older adults with and without HIV: a cohort study from Mbarara, Uganda.

Background and Objectives Perceived HIV stigma is a persistent challenge, contributing to reduced antiretroviral therapy adherence among people with HIV. Although perceived stigma declined with treatment rollout, it is unknown if that trend has continued, particularly among the growing population of...

Full description

Bibliographic Details
Published in:Gerontologist Vol. 66; no. 7; pp. 1 - 12
Main Authors: Mandell, Chase, Seeley, Janet, Maling, Samuel, Nakasujja, Noeline, Paul, Robert, Reynolds, Zahra, Passell, Eliza, Ritchie, Christine S, Hoeppner, Susanne S, Atwiine, Flavia
Format: Article
Published: Oxford University Press / USA Jul2026
Subjects:
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=195281446&site=ehost-live
header:
  @attributes:
    shortDbName: ssf
    uiTerm: 195281446
    longDbName: Social Sciences Full Text (H.W. Wilson)
    uiTag: AN
  controlInfo:
    bkinfo:
    jinfo:
      jid:
        00169013
        GET
      jtl: Gerontologist
      issn: 00169013
      maglogo: N
    pubinfo:
      dt: Jul2026
      vid: 66
      iid: 7
      pid: 622
      pub: Oxford University Press / USA
    artinfo:
      ui:
        195281446
        10.1093/geront/gnag119
      ppf: 1
      ppct: 11
      formats:
      tig:
        atl: Long-term trends in HIV-related stigma among older adults with and without HIV: a cohort study from Mbarara, Uganda.
      aug:
        au:
          Mandell, Chase
          Seeley, Janet
          Maling, Samuel
          Nakasujja, Noeline
          Paul, Robert
          Reynolds, Zahra
          Passell, Eliza
          Ritchie, Christine S
          Hoeppner, Susanne S
          Atwiine, Flavia
        affil:
          Medical Practice Evaluation Center, Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, United States
          Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, United KingdomSocial Science Unit, Africa Health Research Institute, Durban, South Africa
          Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda
          Department of Psychiatry, Makerere University, Kampala, Uganda
          Department of Psychological Sciences, University of Missouri–St Louis, St Louis, Missouri, United States
          Division of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United StatesDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, United States
          Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United StatesDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States
          Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda
      su:
        Uganda
        Self-evaluation
        Quality of life
        Social stigma
        Old age
        Statistical models
        Research funding
        Cronbach's alpha
        Viral load
        T cells
        Questionnaires
        Multiple regression analysis
        Descriptive statistics
        Mann Whitney U Test
        Chi-squared test
        Psychology of HIV-positive persons
        Longitudinal method
        RNA
        Conceptual structures
        Data analysis software
        Confidence intervals
      sug:
        subj:
          Self-evaluation
          Quality of life
          Social stigma
          Old age
          Uganda
          Statistical models
          Research funding
          Cronbach's alpha
          Viral load
          T cells
          Questionnaires
          Multiple regression analysis
          Descriptive statistics
          Mann Whitney U Test
          Chi-squared test
          Psychology of HIV-positive persons
          Longitudinal method
          RNA
          Conceptual structures
          Data analysis software
          Confidence intervals
      keyword:
        africa south of the sahara
        aged
        copyrightHolder:The Gerontological Society of America
        copyrightYear:2026
        hiv
        HIV/AIDS
        https://dx.doi.org/10.1093/geront/gnag119
        inLanguage:en
        Longitudinal analysis
        publisher:Oxford University Press
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42213586/
        social stigma
        Stigmatization
        Sub-Saharan Africa
        uganda
        africa south of the sahara
        aged
        copyrightHolder:The Gerontological Society of America
        copyrightYear:2026
        hiv
        HIV/AIDS
        https://dx.doi.org/10.1093/geront/gnag119
        inLanguage:en
        Longitudinal analysis
        publisher:Oxford University Press
        sameAs:https://pubmed.ncbi.nlm.nih.gov/42213586/
        social stigma
        Stigmatization
        Sub-Saharan Africa
        uganda
      ab: Background and Objectives Perceived HIV stigma is a persistent challenge, contributing to reduced antiretroviral therapy adherence among people with HIV. Although perceived stigma declined with treatment rollout, it is unknown if that trend has continued, particularly among the growing population of older adults with HIV in sub-Saharan Africa. Research Design and Methods We analyzed data from 6 waves of data collection over 9 years in a cohort of older adults with and without HIV in Uganda. Participants completed a standardized 15-item perceived stigma questionnaire at each visit. We fitted generalized estimating equations to characterize trends in stigma over time, stratified by HIV serostatus. Results We analyzed follow-up data on 271 individuals with a median duration of 9 years (interquartile range [IQR]: 8–9). Approximately 51% were people with HIV, 47% were women, and the median age was 51 years (IQR: 48–55) at baseline. Compared to 2015, perceived stigma decreased among people with HIV through 2018 with further declines up to 2024 (p  < .05 for all comparisons). By contrast, among people without HIV, after a decrease from 2015 to 2018 (p  < .05), perceived stigma increased substantially, such that levels in 2022 were similar to 2015 (p  = .92). Discussion and Implications Perceived stigma has decreased over the past decade among older people with HIV but remains at a similar level in the early 2020s as in 2015 among those without HIV in Uganda. These findings highlight the importance of maintaining HIV sensitization efforts in the general population, even in an era with decreasing HIV-related deaths.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
    refInfo:
    copyright:
      @attributes:
        flag: N
    holdings:
      @attributes:
        islocal: N