An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022.
Objectives. To examine geospatial polysubstance use overdose typologies and socio-structural determinants among overdose decedents in Cook County, Illinois, from 2017 to 2022. Methods. Decedents' addresses were geocoded and aggregated to census tract level (n = 1331). We conducted latent profile ana...
| Publicado en: | American Journal of Public Health Vol. 116; no. 8; pp. 1210 - 1220 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Public Health Association
Aug2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=195376218&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 195376218 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00900036 APH jtl: American Journal of Public Health issn: 00900036 maglogo: N pubinfo: dt: Aug2026 vid: 116 iid: 8 pid: 44 pub: American Public Health Association artinfo: ui: 195376218 10.2105/AJPH.2026.308446 ppf: 1210 ppct: 10 formats: tig: atl: An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022. aug: au: Cadet, Kechna Martins, Silvia S. Nesoff, Elizabeth D. affil: Columbia University Vagelos College of Physicians and Surgeons, New York, NY.; Mailman School of Public Health, Columbia University, New York, NY. Columbia Mailman School of Public Health, New York, NY. Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. su: Illinois Substance abuse Cross-sectional method Cocaine Social determinants of health Residential patterns Socioeconomic factors Census Sex distribution Population geography Drugs of abuse Drug overdose Research funding Probability theory Logistic regression analysis Descriptive statistics Global Positioning System Heroin Odds ratio Confidence intervals Comparative studies Data analysis software Fentanyl sug: subj: Substance abuse Cross-sectional method Cocaine Social determinants of health Residential patterns Socioeconomic factors Census Sex distribution Population geography Drugs of abuse Illinois Pharmaceutical and medicine manufacturing Medicinal and Botanical Manufacturing Drug overdose Research funding Probability theory Logistic regression analysis Descriptive statistics Global Positioning System Heroin Odds ratio Confidence intervals Comparative studies Data analysis software Fentanyl ab: Objectives. To examine geospatial polysubstance use overdose typologies and socio-structural determinants among overdose decedents in Cook County, Illinois, from 2017 to 2022. Methods. Decedents' addresses were geocoded and aggregated to census tract level (n = 1331). We conducted latent profile analysis to identify census tract profiles based on overdose fatality rates per 1000 census tract population across 9 drug types (alcohol, fentanyl, prescription opioids, heroin, cocaine, benzodiazepines, xylazine, methamphetamine/amphetamine, and other drugs). We used Bayesian spatial multinomial logistic regression to determine what census tract socio-structural determinants could predict polysubstance profile membership. Results. Three clusters of polysubstance use—low, moderate, and high—emerged with fentanyl, cocaine, and heroin dominating all clusters. In the adjusted model, census tracts with lower median household income were associated with increased odds of belonging to the moderate polysubstance use profile (odds ratio [OR] = 0.90; 95% Bayesian credible interval [CrI] = 0.85, 0.96) compared with the referent group. Also, census tracts with high Black isolation (quartile 4: OR = 2.93; 95% CrI = 1.44, 6.02) and higher population density (OR = 1.24; 95% CrI = 1.13, 1.37) were more likely to belong in the high polysubstance use profiles. Conclusions. Findings support the need for targeted resources tailored for particular neighborhoods. (Am J Public Health. 2026;116(8):1210–1219. https://doi.org/10.2105/AJPH.2026.308446) pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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