Peristomal Pyoderma Gangrenosum Related to Systemic Lupus Erythematosus: A Case Study.

BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a rare complication of peristomal skin. It is difficult to manage, and there are no guidelines for treatment. This case study describes the management of a patient with PPG while taking corticosteroids and cyclosporine as chronic therapy for syste...

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Published in:Journal for Healthcare Quality: Promoting Excellence in Healthcare Vol. 50; no. 3; pp. 342 - 346
Main Authors: Denti, Francesco Carlo, Bancea, Dorina, Vidotto, Giulia, Maglio, Andrea, Brambilla, Davide, Rosa, Debora, Villa, Giulia
Format: Journal Article
Published: Lippincott Williams & Wilkins Jul-Sep2026
Online Access:View this record in EBSCOhost
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      dt: Jul-Sep2026
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      pub: Lippincott Williams & Wilkins
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        atl: Peristomal Pyoderma Gangrenosum Related to Systemic Lupus Erythematosus: A Case Study.
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          Denti, Francesco Carlo
          Bancea, Dorina
          Vidotto, Giulia
          Maglio, Andrea
          Brambilla, Davide
          Rosa, Debora
          Villa, Giulia
        affil: Francesco Carlo Denti, RN, MScN, IRCCS San Raffaele Institute, Milan, Italy.
      sug:
      ab: BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a rare complication of peristomal skin. It is difficult to manage, and there are no guidelines for treatment. This case study describes the management of a patient with PPG while taking corticosteroids and cyclosporine as chronic therapy for systemic lupus erythematosus (SLE). CASE: Mrs. T had SLE and a colostomy and developed PPG that was unresponsive to previous treatment. She was successfully treated with a barrier film, a topical corticosteroid, and an alginate dressing. CONCLUSION: The synergistic use of a barrier film, a topical corticosteroid, and an alginate proved to be effective for the management of PPG lesions in SLE.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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