Co-design, implementation, and evaluation of a nested diabetes model of care for adults with cystic fibrosis: a mixed methods pre-post implementation study.

Background: Cystic fibrosis (CF) is a genetic disease with increasing life expectancy due to advances in treatment. However, this increased life expectancy has led to new health challenges, especially diabetes. Nearly 25% of adults with CF develop diabetes, but only a minority receive endocrinology...

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Publicado en:JBI Evidence Implementation Vol. 24; no. 3; pp. 547 - 559
Autores principales: Kumar, Shanal, Smith, Daniel, Moore, Vanessa, Matson, Angela
Formato: pictorial research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Jul2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2026
      vid: 24
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      pid: 433
      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        195416593
        195416593
        195416593
        10.1097/XEB.0000000000000551
        195416593
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        atl: Co-design, implementation, and evaluation of a nested diabetes model of care for adults with cystic fibrosis: a mixed methods pre-post implementation study.
      aug:
        au:
          Kumar, Shanal
          Smith, Daniel
          Moore, Vanessa
          Matson, Angela
        affil: The Adult Cystic Fibrosis Centre (ACFC), The Prince Charles Hospital, Brisbane, Qld, Australia
      sug:
        subj:
          Cystic Fibrosis Therapy
          Diabetes Mellitus Therapy
          Multidisciplinary Care Team
          Health Care Delivery, Integrated
          Program Implementation
          Program Evaluation
          Human
          Adult
          Multimethod Studies
          Validation Studies
          Comparative Studies
          Descriptive Statistics
          Pretest-Posttest Design
          Queensland
          Academic Medical Centers
          Hospital Programs
          Thematic Analysis
          Continuous Glucose Monitoring
          Biological Markers
          Glycated Hemoglobin
          Forced Expiratory Volume
          Implementation Science
          Funding Source
          Adult: 19-44 years
      ab: Background: Cystic fibrosis (CF) is a genetic disease with increasing life expectancy due to advances in treatment. However, this increased life expectancy has led to new health challenges, especially diabetes. Nearly 25% of adults with CF develop diabetes, but only a minority receive endocrinology care. Objective: This study aimed to co-design, implement, and evaluate a nested diabetes model of care (MOC) for adults with CF and diabetes in a single tertiary adult CF center in Australia. Methods: We used several implementation frameworks to co-design the MOC with consumer and provider end-users. Following MOC implementation, we used database-driven analytics to evaluate changes in the primary clinical outcome (HbA1c) pre and post study at 1 year. A mixed methods approach was used to evaluate secondary clinical and non-clinical outcomes. Results: The MOC promoted multidisciplinary collaboration and streamlined patient journeys, leading to high engagement. Thus, 76.7% of the entire CF cohort with confirmed diabetes was reviewed within the first year of operationalization. Engagement with the MOC was associated with a statistically significant decline in HbA1c (−0.54% vs +0.33%, p- value 0.004) and a 0.22% [95% CI 0.19 −0.32] per month increment in percent predicted forced expiratory volume (ppFEV1). Conclusion: Our co-designed MOC demonstrated high engagement as well as improving glycemic management and lung function in adults with CF and diabetes. Our approach to CF diabetes care may reduce the treatment burden in the order of initiating a new diabetes medication while concurrently enhancing end-user experiences of health care. http://links.lww.com/IJEBH/A473
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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