Bridging Gaps in Hepatitis B Virus Prevention: A Systematic Review and Meta-Analysis of Knowledge, Attitudes and Preventive Practices in Ethiopia.

Background: Hepatitis B virus (HBV) infection continues to pose a significant global health challenge, with prevention efforts heavily dependent on individuals' knowledge, attitudes, and practices. Recognizing the critical role of comprehensive data in shaping policy, we sought to pool estimates fro...

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Publicado en:Health Services Insights Vol. 19; pp. 1 - 23
Autores principales: Woldegeorgis, Beshada Zerfu, Ekubazgi, Kinfe Woldu, Urgesa, Ermiyas Abera, Kassie, Gizachew Ambaw, Gebrekidan, Amanuel Yosef, Asgedom, Yordanos Sisay
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Sage Publications Inc. 7/17/2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/17/2026
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        atl: Bridging Gaps in Hepatitis B Virus Prevention: A Systematic Review and Meta-Analysis of Knowledge, Attitudes and Preventive Practices in Ethiopia.
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          Woldegeorgis, Beshada Zerfu
          Ekubazgi, Kinfe Woldu
          Urgesa, Ermiyas Abera
          Kassie, Gizachew Ambaw
          Gebrekidan, Amanuel Yosef
          Asgedom, Yordanos Sisay
        affil: Division of Gastroenterology and Hepatology, Department of Internal Medicine, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia
      sug:
        subj:
          Hepatitis B Prevention and Control
          Attitude to Health
          Health Knowledge
          Health Behavior
          Human
          Systematic Review
          Meta Analysis
          Male
          Female
          PubMed
          Embase
          Descriptive Statistics
          Data Analysis Software
          Checklists
          Confidence Intervals
          Odds Ratio
          Illiteracy
          Male
          Female
      ab: Background: Hepatitis B virus (HBV) infection continues to pose a significant global health challenge, with prevention efforts heavily dependent on individuals' knowledge, attitudes, and practices. Recognizing the critical role of comprehensive data in shaping policy, we sought to pool estimates from primary studies conducted across various regions of Ethiopia. Methods: Full text studies published in English from December 31st 2010 to May 31st, 2025 were identified through searches in the PubMed, Embase, Web of Science, African Journals Online, Google Scholar, and Scopus databases using the medical subject headings and text words. The protocol was registered in the PROSPERO and the results were reported accordance with the PRISMA 2020. The heterogeneity was evaluated graphically and using statistical methods. Publication bias was assessed with a funnel plot and Egger's regression (significant at P ≤ 0.05). A random-effects meta-analysis was performed to calculate the pooled estimates. Results: The search identified 980 records and 26 studies met the eligibility criteria and were included. The pooled prevalence of a good level of knowledge, favorable attitudes, and good prevention practices was 47.45% (95% confidence interval (CI) 36.53, 58.36), 50.48% (95% CI 38.65, 62.30), and 36.22% (95% CI 27.22, 45.23), respectively. In the subgroup analysis, a good level of knowledge among barbers was only 11.14% (95% CI 8.55–13.74). Being a rural resident (pooled odds ratio (pOR) = 2.25, 95% CI 1.39, 3.63), illiterate (pOR = 2.22, 95% CI 1.30, 3.76), having poor knowledge (pOR = 2.13, 95% CI 1.56, 2.91), and having unfavorable attitudes (pOR = 3.56, 95% CI 1.17, 10.81) were significantly associated with poor HBV prevention practices. Conclusions and recommendations: The results revealed elevated gaps in knowledge, attitudes, and practices related to the prevention of HBV infection. These results highlight the urgent need to strengthen public awareness campaigns, integrate HBV modules into adult literacy programs, and develop culturally sensitive communication strategies to counter cultural myths that hinder positive attitudes and practices toward HBV prevention and care, establish mobile clinics for rural communities, promote adult education programs for rural communities in local languages.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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