مرور نظام مند مطالعات گزارش موردی و سریهای موردی میکروسپوریدیوز چشمی در انسان.
Introduction: Microsporidia, a rare opportunistic organism often misidentified in corneal infections, constitutes approximately 0.4% of microbial keratitis cases in certain populations. The aim of the present study is to conduct a systematic analysis of case reports and case series of ocular microsp...
| Publicado en: | Pars Journal of Medical Sciences Vol. 23; no. 4; pp. 6 - 21 |
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| Autores principales: | , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Journal of Jahrom University of Medical Sciences
Autumn2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195482640&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195482640 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27170284 N98H jtl: Pars Journal of Medical Sciences issn: 27170284 maglogo: N pubinfo: dt: Autumn2025 vid: 23 iid: 4 pid: 70438 pub: Journal of Jahrom University of Medical Sciences place: , <Blank> artinfo: ui: 195482640 195482640 195482640 10.22034/pjms.2026.2085668.1276 195482640 ppf: 6 ppct: 15 formats: fmt: @attributes: type: P tig: atl: مرور نظام مند مطالعات گزارش موردی و سریهای موردی میکروسپوریدیوز چشمی در انسان. aug: au: علی تقی پور ا امیر عبدلی حسن جعفری سعید بهادری ۲ مهد امیرحسین نصیری پ affil: گروه انگل شناسی و قارچ شناسی پزشکی دانشکده پزشکی دانشگاه علوم پزشکی جهرم، جهرم ایران. sug: subj: Eye Infections, Fungal Diagnosis Mycoses Diagnosis Eye Infections, Fungal Drug Therapy Treatment Outcomes Human Systematic Review Subject Headings PubMed Medline Embase Cochrane Library Abstracts Eye Infections, Fungal Risk Factors Risk Assessment Occupational Exposure Adverse Effects Environmental Exposure Adverse Effects Water Pollution Adverse Effects Environmental Pollution Adverse Effects Adrenal Cortex Hormones Adverse Effects Diabetes Mellitus Complications Kidney Transplantation Adverse Effects Disease Attributes Photophobia Vision Disorders Cornea Pathology Recovery Corneal Transplantation Recurrence Graft Rejection Descriptive Statistics ab: Introduction: Microsporidia, a rare opportunistic organism often misidentified in corneal infections, constitutes approximately 0.4% of microbial keratitis cases in certain populations. The aim of the present study is to conduct a systematic analysis of case reports and case series of ocular microsporidiosis in humans for the first time. Methods & Materials: This systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Defined terms as Medical Subject Headings (MeSH) keywords were searched from 2017 to the end of 2023 in the scientific databases PubMed/MEDLINE, Embase, Web of Science and Cochrane Library. Case reports and case series in English or English abstracts related to ocular microsporidiosis in humans were included in the study. Results: Finally, 28 studies including 426 participants were systematically reviewed. Several risk factors were identified, such as occupational or environmental exposure to contaminated water and soil, corticosteroid use, and underlying diseases (e.g., diabetes or kidney transplantation). The main clinical features included redness, blurred vision, and photophobia, accompanied by varying pathological findings in the cornea. Also, treatment outcomes were diverse, ranging from full recovery with medication to the need for penetrating keratoplasty (corneal transplantation) in resistant cases and instances of disease recurrence and graft rejection were also observed. Conclusion: This review demonstrated that ocular microsporidiosis is associated with a broad spectrum of clinical manifestations and treatment outcomes. Therefore, successful management of this infection necessitates a meticulous assessment of the patient’s risk factors and the customization of a specific treatment plan, ranging from pharmacotherapy to surgical intervention, to prevent recurrence and achieve the best visual outcome. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: Persian refInfo: holdings: @attributes: islocal: N |
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