Characterizing superficial cerebral cortical venous anatomy for endovascular device implantation: a cross- sectional imaging study.

Background Neurovascular electronic devices, including brain- computer interfaces (BCIs), offer a minimally invasive approach to diagnosing and treating neurological disorders. Implanting BCIs in superficial cortical veins, owing to their proximity to sensorimotor cortices, may improve motor functio...

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Publicado en:Journal of NeuroInterventional Surgery Vol. 18; no. 7; pp. 1710 - 1718
Autores principales: Brannigan, Jamie, Kian, Azadeh, Eiber, Calvin, Tarigoppula, Venkata S. Aditya, Bogard, Jillian, Siddiqui, Adnan H., Rind, Gil, Berenstein, Alejandro, Majidi, Shahram, Oxley, Thomas J.
Formato: diagnostic images research tables/charts Journal Article
Publicado: BMJ Publishing Group Jul2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2026
      vid: 18
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      pub: BMJ Publishing Group
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        10.1136/jnis-2025-023532
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        atl: Characterizing superficial cerebral cortical venous anatomy for endovascular device implantation: a cross- sectional imaging study.
      aug:
        au:
          Brannigan, Jamie
          Kian, Azadeh
          Eiber, Calvin
          Tarigoppula, Venkata S. Aditya
          Bogard, Jillian
          Siddiqui, Adnan H.
          Rind, Gil
          Berenstein, Alejandro
          Majidi, Shahram
          Oxley, Thomas J.
        affil: Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
      sug:
        subj:
          Cerebral Cortex Blood Supply
          Cerebral Veins Anatomy and Histology
          Blood Vessel Prosthesis
          Endovascular Procedures
          Brain-Computer Interfaces
          Prosthesis Design
          Preoperative Care
          Human
          Exploratory Research
          Minimally Invasive Procedures
          Retrospective Design
          Record Review
          Cerebral Veins Radiography
          Phlebography Methods
          Tomography, X-Ray Computed
          Magnetic Resonance Imaging
          Magnetic Resonance Angiography
          Hospitals
          New York
          Cross Sectional Studies
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background Neurovascular electronic devices, including brain- computer interfaces (BCIs), offer a minimally invasive approach to diagnosing and treating neurological disorders. Implanting BCIs in superficial cortical veins, owing to their proximity to sensorimotor cortices, may improve motor function restoration. However, marked anatomical variability and the complex anteriorly directed connection with the superior sagittal sinus (SSS) complicate device navigation. This exploratory study aimed to characterize cortical venous anatomy to inform device design and procedural planning. Methods Retrospective imaging data from 25 patients were analyzed using magnetic resonance venography (MRV) and computed tomography venography (CTV). Vessel segmentation and analysis quantified parameters such as vein presence, diameter, length, angulation, and tortuosity. In 12 patients, T1- weighted magnetic resonance imaging (MRI) was used to extract cortical gyri and sulci, assessing vessel--cortex relationships. Results The superior anastomotic vein (vein of Trolard) was identified bilaterally in 84% of patients, with a mean entrance diameter of 4.4 mm. Frequent transient constrictions (<2 mm) were reported. The precentral vein was present bilaterally in 52% of cases. Most cortical veins exhibited take- off angles >90 degrees from the SSS, presenting challenges for endovascular navigation, with overall considerable anatomical variability observed. Conclusion The vein of Trolard shows promise as a target for endovascular BCIs given its consistent presence and favorable dimensions. Nonetheless, constrictions and steep angulation at the SSS confluence pose challenges for device deployment. A new framework is necessary for the classification of cortical venous anatomy, to guide patient selection and procedural planning, which will require further development and validation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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