NegotiAge—An AI‐Based Caregiver Negotiation Training: Results From the Multiphase Optimization Strategy (MOST) Trial.

Background: Family caregivers experience conflicts in caring for people with Alzheimer's dementia (PWD; e.g., siblings disagreeing, advocating with providers, PWD refusing assistance). Subsequently, family caregivers experience frustration, burden, and stress. Furthermore, these caregivers rarely re...

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Published in:Journal of the American Geriatrics Society Vol. 74; no. 7; pp. 2032 - 2041
Main Authors: Ramirez‐Zohfeld, Vanessa, Murawski, Alaine, Jobin, Celie, Olvera, Charles, Mell, Johnathan, Brett, Jeanne, Gratch, Jonathan, Tschoe, Marianne, Pfammatter, Angela F., Lindquist, Lee A.
Format: Article
Published: Wiley-Blackwell Jul2026
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Online Access:View this record in EBSCOhost
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      dt: Jul2026
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      pub: Wiley-Blackwell
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        10.1111/jgs.70546
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        atl: NegotiAge—An AI‐Based Caregiver Negotiation Training: Results From the Multiphase Optimization Strategy (MOST) Trial.
      aug:
        au:
          Ramirez‐Zohfeld, Vanessa
          Murawski, Alaine
          Jobin, Celie
          Olvera, Charles
          Mell, Johnathan
          Brett, Jeanne
          Gratch, Jonathan
          Tschoe, Marianne
          Pfammatter, Angela F.
          Lindquist, Lee A.
        affil:
          Division of Geriatrics, Northwestern University, Feinberg School of Medicine, Chicago Illinois,, USA
          University of Central Florida, Orlando Florida,, USA
          Center on Dispute Resolutions, Northwestern University, Kellogg School of Business, Chicago Illinois,, USA
          Vanderbilt University, Nashville Tennessee,, USA
          University of Tennessee Knoxville, Knoxville Tennessee,, USA
      su:
        Health literacy
        World Wide Web
        Elder care
        Computer simulation
        Empathy
        Self-efficacy
        Negotiation
        Health
        Families
        Randomized controlled trials
        Problem solving
        Caregivers
        Analysis of variance
        Affect (Psychology)
        Conflict management
        Avoidance (Psychology)
        Anxiety prevention
        Statistical models
        Emotion regulation
        Data analysis
        Research funding
        T-test (Statistics)
        Statistical sampling
        Questionnaires
        Descriptive statistics
        Burden of care
        Surveys
        Pre-tests & post-tests
        Avatars (Virtual reality)
        Research methodology
        Statistics
        Health outcome assessment
        Data analysis software
        Application software
        Dementia patients
        Video recording
        User interfaces
      sug:
        subj:
          Health literacy
          World Wide Web
          Elder care
          Computer simulation
          Empathy
          Self-efficacy
          Negotiation
          Health
          Families
          Randomized controlled trials
          Problem solving
          Caregivers
          Analysis of variance
          Affect (Psychology)
          Conflict management
          Avoidance (Psychology)
          Continuing Care Retirement Communities
          Software publishers (except video game publishers)
          Software Publishers
          Custom Computer Programming Services
          Marketing Research and Public Opinion Polling
          Internet Publishing and Broadcasting and Web Search Portals
          Anxiety prevention
          Statistical models
          Emotion regulation
          Data analysis
          Research funding
          T-test (Statistics)
          Statistical sampling
          Questionnaires
          Descriptive statistics
          Burden of care
          Surveys
          Pre-tests & post-tests
          Avatars (Virtual reality)
          Research methodology
          Statistics
          Health outcome assessment
          Data analysis software
          Application software
          Dementia patients
          Video recording
          User interfaces
      keyword:
        artificial intelligence
        conflict resolution
        family caregivers
        negotiation
        artificial intelligence
        conflict resolution
        family caregivers
        negotiation
      ab: Background: Family caregivers experience conflicts in caring for people with Alzheimer's dementia (PWD; e.g., siblings disagreeing, advocating with providers, PWD refusing assistance). Subsequently, family caregivers experience frustration, burden, and stress. Furthermore, these caregivers rarely receive formal conflict resolution training to ameliorate these concerns. We developed NegotiAge—an artificial intelligence (AI)‐based negotiation training intervention that teaches caregivers how to resolve conflicts and provides the opportunity to practice negotiating with online avatars in real‐world conflicts. We sought to optimize the potency and test the early effect of NegotiAge on family caregivers following the multiphase optimization strategy (MOST). Participants, Design, Setting: National randomized factorial trial of NegotiAge with family caregivers of PWD (> 65 years). Caregivers were randomized to one of eight conditions and variables/outcomes assessed at baseline and 1 month following NegotiAge. The mixed methods project used dependent sample t‐tests (quantitative) and constant comparative analysis (qualitative). Results: Across 23 states, 125 family caregivers (mean‐age 54 years, 77% female) completed the study. Participants experienced significantly less caregiver burden (−3.24, p < 0.002) and negative affect (−2.1, p < 0.0001) between baseline and 1 month following. Those receiving two or more exercises experienced further significant burden reduction (−5.28, p < 0.04). Qualitative analyses supported these findings: "There was a time when my mother was crying. Because of the training I was able to calm her."; "When we have a conflict, I focus on the interest of both of us–helped tremendously." In the month following, 54% (n = 67) of participants experienced conflicts and 74% (n = 93) applied skills learned. Among utilizers, there was a significant decrease in forcing behaviors (−1.24, p < 0.0001). Conclusions: NegotiAge, an AI‐based negotiation training intervention, significantly reduced burden and improved negative affect among family caregivers. Engaging in more negotiation exercises further reduced burden. NegotiAge has the potential to improve the lives of caregivers and PWD. Further testing is needed to determine the direct impact on older adults and long‐term effects. Trial Registration: ClinicalTrials.gov identifier: NCT04837937 Summary: Key Points ○Family caregivers experience conflicts when interacting with and advocating for their older adults with Alzheimer's dementia (PWD). NegotiAge is an AI‐based online negotiation training program that teaches family caregivers how to resolve conflicts and enables them to practice negotiating with avatars receiving real time feedback on how to improve their skills.○Using the multiphase optimization strategy (MOST) framework, we conducted a national randomized factorial trial with four different NegotiAge exercises with family caregivers of PWD (n = 125, 23 states) with data collection at baseline, immediately, and 1 month following completion of NegotiAge.○One month after completing NegotiAge, family caregivers experienced significantly less burden (p < 0.005), less negative affect (p < 0.05), and qualitative analysis revealed the family caregivers had life‐changing experiences with their PWD following training.Why Does This Paper Matter? ○Family caregivers are frequently unprepared to handle conflicts that occur when working with and advocating for their older adult loved ones. Participating in NegotiAge, an online AI‐based negotiation program, reduced caregiver burden and improved negative affect after 1 month following use. Scalable interventions for caregivers that reduce burden are efficient (around 45 min) and can be completed on the users' schedule are vital to aiding family caregivers and improving the care of PWD.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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