Transcriptomic Stratification Reveals an FRS2-Associated, Proliferation-Independent Phenotype in MDM2-High Sarcomas.

Simple Summary: Sarcomas with murine double minute 2 (MDM2) amplification are promising candidates for targeted therapy. However, their treatment response remains limited. To further investigate this limitation, we analyzed a publicly available dataset of 310 soft tissue sarcomas and examined the re...

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Publicado en:	Current Oncology Vol. 33; no. 7; pp. 438 - 448
Autores principales:	Sakai, Takao, Aiba, Hisaki, Yamaguchi, Makoto, Hagiwara, Koji, Murakami, Hideki, Kimura, Hiroaki
Formato:	Journal Article
Publicado:	MDPI Jul2026
Acceso en línea:	Ver este registro en EBSCOhost