Metabolomic Discoveries for Traditional Chinese Medicine Efficacy in Alzheimer′s Disease.
Alzheimer′s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and behavioral alterations. However, the complex etiology and pathogenesis of AD have thus far precluded the development of satisfactory therapeutic agents. Traditional Chinese...
| Publicado en: | BioMed Research International Vol. 2026; pp. 1 - 25 |
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| Autores principales: | , , , , , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
7/31/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195833611&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195833611 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 7/31/2026 vid: 2026 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 195833611 195833611 195833611 10.1155/bmri/2455800 195833611 ppf: 1 ppct: 24 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Metabolomic Discoveries for Traditional Chinese Medicine Efficacy in Alzheimer′s Disease. aug: au: Sun, Huimin Huang, Dongxuan Yang, Fang Zhang, Pengfei Yang, Dexin Zeng, Changchun Gurumallesh Prabu, Poorani affil: Department of Medical Laboratory,, Shenzhen Longhua District Central Hospital,, Shenzhen, Guangdong,, China, glyy.org sug: subj: Alzheimer's Disease Drug Therapy Medicine, Chinese Traditional Drugs, Chinese Herbal Pharmacodynamics Drug Efficacy Metabolomics Alzheimer's Disease Pathology Brain Metabolism Urine Metabolism Blood Metabolism Feces Metabolism Sphingolipids Metabolism Phospholipids Metabolism Linoleic Acids Metabolism Arachidonic Acids Metabolism Amino Acids Metabolism Purines Metabolism Lipids Metabolism Arginine Metabolism Proline Metabolism Gut Microbiota Metabolism Brain-Gut Axis ab: Alzheimer′s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and behavioral alterations. However, the complex etiology and pathogenesis of AD have thus far precluded the development of satisfactory therapeutic agents. Traditional Chinese medicine (TCM) has garnered increasing recognition for its potential in AD management due to its multicomponent, multitarget therapeutic strategy. Metabolomics, an advanced analytical methodology for investigating metabolic alterations in biological systems, has yielded significant insights into both the therapeutic efficacy and mechanistic underpinnings of TCM interventions for AD. This review synthesizes recent metabolomic findings associated with TCM approaches to AD treatment, identifying key metabolic pathways across diverse biological specimens, including brain tissue, blood, urine, and feces. Through systematic elucidation of these metabolic networks, metabolomics offers substantial potential to facilitate the advancement of TCM‐derived therapeutics for AD, potentially enhancing global patient outcomes. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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