Unsaturated lactones from Aspergillus ochraceopetaliformis.

A new α,β-unsaturated lactone, 2-(1-hydroxy-2-methylpropyl)-4-isopropylfuran-1(4H)-one (1), along with nine known compounds (2-10), was isolated from Aspergillus ochraceopetaliformis. The structure of compound 1 was elucidated based on comprehensive spectroscopic analysis, including 1D and 2D NMR (H...

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Publicado en:Natural Product Research Vol. 40; no. 15; pp. 4553 - 4557
Autores principales: Bai, Jing-Jie, Pan, Hong-Qian, Liu, Qiong, Li, Duo-Xiu, Zhu, Bai-Chuan, Zhang, Ying-Ming, Zhao, Ai-Hong, Yuan, Cheng-Shan
Formato: Journal Article
Publicado: Taylor & Francis Ltd Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2026
      vid: 40
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      pub: Taylor & Francis Ltd
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        atl: Unsaturated lactones from Aspergillus ochraceopetaliformis.
      aug:
        au:
          Bai, Jing-Jie
          Pan, Hong-Qian
          Liu, Qiong
          Li, Duo-Xiu
          Zhu, Bai-Chuan
          Zhang, Ying-Ming
          Zhao, Ai-Hong
          Yuan, Cheng-Shan
        affil: Laboratory for Design and Synthesis of Natural Medicines and Chemical Small Molecule Drugs, School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, China
      sug:
      ab: A new α,β-unsaturated lactone, 2-(1-hydroxy-2-methylpropyl)-4-isopropylfuran-1(4H)-one (1), along with nine known compounds (2-10), was isolated from Aspergillus ochraceopetaliformis. The structure of compound 1 was elucidated based on comprehensive spectroscopic analysis, including 1D and 2D NMR (HSQC, COSY, HMBC), and HR-ESI-MS spectrometry. The absolute configuration was determined by comparison of the experimental and time-dependent density functional theory (TDDFT)-calculated electronic circular dichroism (ECD) spectra. Herein, we report the isolation, structure elucidation, and cytotoxic evaluation of the isolated compounds.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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