Effect of an evidence-based modified developmental physiotherapy intervention on muscle tone, motor functions, and trunk control in a child with hereditary spastic paraplegia type 47: A case report.

Background: Most current studies on Hereditary Spastic Paraplegia (HSP) focus on adolescents and adults. There is a lack of research on the effectiveness of structured, evidence-based developmental physiotherapy during early childhood. While early intervention strategies for children with motor deve...

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Publicado en:Physiotherapy Theory & Practice Vol. 42; no. 8; pp. 1120 - 1130
Autor principal: Sırrı, Bayram
Formato: case study research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2026
      vid: 42
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      pub: Taylor & Francis Ltd
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        atl: Effect of an evidence-based modified developmental physiotherapy intervention on muscle tone, motor functions, and trunk control in a child with hereditary spastic paraplegia type 47: A case report.
      aug:
        au: Sırrı, Bayram
        affil: Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Muş Alparslan University, Muş Merkez, Muş, Türkiye
      sug:
        subj:
          Physical Therapy Methods
          Motor Activity In Infancy and Childhood
          Torso Physiology
          Spastic Paraplegia, Hereditary Complications
          Child Development
          Home Health Care
          Spastic Paraplegia, Hereditary Rehabilitation
          Treatment Outcomes
          Human
          Motor Skills
          Family Centered Care
          Early Intervention
          Medical Practice, Evidence-Based
          Infant
          Muscle, Skeletal Physiology
          Parental Attitudes
          Consent
          Pretest-Posttest Design
          Muscle, Skeletal
          Program Implementation
          Program Evaluation
          Descriptive Statistics
          Standing
          Scales
          Infant: 1-23 months
      ab: Background: Most current studies on Hereditary Spastic Paraplegia (HSP) focus on adolescents and adults. There is a lack of research on the effectiveness of structured, evidence-based developmental physiotherapy during early childhood. While early intervention strategies for children with motor development delays offer a useful framework, no specific guidelines have been developed for early physiotherapy in HSP. This report aimed to describe the effects of a home-based, evidence-based developmental physiotherapy approach in a child diagnosed with HSP Type 47 (SPG47). Case Description: A two-year-old child with SPG47 participated with parental consent. Before intervention, the child was unable to stand up using support or take more than a few side steps. Muscle tone, motor function, functional level, and trunk control were assessed using MAS, GMFCS, GMFM-66, and SATCo, respectively. Interventions: A developmental physiotherapy program based on current evidence was implemented at home for 2 hours daily over 8 weeks, with daily home implementation by the family. The intervention was grounded in family-centered care principles and evidence-based early developmental physiotherapy, tailored to the child's clinical presentation. Outcomes: After the program, GMFM-66 increased by 7.2%. The child gained the ability to stand independently and take more than five side steps. MAS scores improved, SATCo increased from level 6 to 7, and GMFCS improved from level III to II. Conclusion: In this child with SPG47, an early structured developmental physiotherapy approach was associated with improved motor function and reduced spasticity, supported by motor learning, environmental adaptations, and family involvement. Integrating early intervention principles with HSP-specific considerations enabled targeted task progression and practical home implementation. These findings apply only to this child, and further research is needed to determine whether similar strategies may benefit children with AP4B1-related HSP.
      pubtype: Academic Journal
      doctype:
        case study
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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