Incidence and characteristics of poisonings in older adults with and without dementia: a matched cohort study using Swedish registry data.
Introduction Poisonings are a global public health challenge, especially for older adults with dementia. This study examined the incidence, types and medications involved at the time of poisoning among older people with and without dementia in Sweden. Methods Using linked Swedish national registries...
| Publicado en: | Age & Ageing Vol. 55; no. 7; pp. 1 - 11 |
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| Autores principales: | , , , , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Jul2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=195867366&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 195867366 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Jul2026 vid: 55 iid: 7 pid: 622 pub: Oxford University Press / USA artinfo: ui: 195867366 10.1093/ageing/afag211 ppf: 1 ppct: 10 formats: tig: atl: Incidence and characteristics of poisonings in older adults with and without dementia: a matched cohort study using Swedish registry data. aug: au: Wojt, Ilsa R Hoang, Minh Tuan Wastesson, Jonas W Johnell, Kristina Cairns, Rose Garcia-Ptacek, Sara Eriksdotter, Maria Tan, Edwin C K affil: School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenDepartment of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, SwedenFaculty of Public Health, the University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, SwedenAging and Inflammation Theme, Karolinska University Hospital, Stockholm, Sweden School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaKolling Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney and the Northern Local Health District, St Leonards, New South Wales, AustraliaCharles Perkins Centre, The University of Sydney, Camperdown, New South Wales, Australia su: Sweden Drug side effects Psychiatric drugs Old age Risk assessment Drug toxicity Research funding Reporting of diseases Descriptive statistics Fibrinolytic agents Longitudinal method Kaplan-Meier estimator Dementia Confidence intervals Data analysis software Poisoning Dementia patients Cardiovascular agents Disease complications sug: subj: Drug side effects Psychiatric drugs Old age Sweden Risk assessment Drug toxicity Research funding Reporting of diseases Descriptive statistics Fibrinolytic agents Longitudinal method Kaplan-Meier estimator Dementia Confidence intervals Data analysis software Poisoning Dementia patients Cardiovascular agents Disease complications keyword: adverse drug reaction adverse effects of medication aged copyrightHolder:British Geriatrics Society copyrightYear:2026 dementia https://dx.doi.org/10.1093/ageing/afag211 inLanguage:en medication use older people pharmacoepidemiology poisoning publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/42497097/ adverse drug reaction adverse effects of medication aged copyrightHolder:British Geriatrics Society copyrightYear:2026 dementia https://dx.doi.org/10.1093/ageing/afag211 inLanguage:en medication use older people pharmacoepidemiology poisoning publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/42497097/ ab: Introduction Poisonings are a global public health challenge, especially for older adults with dementia. This study examined the incidence, types and medications involved at the time of poisoning among older people with and without dementia in Sweden. Methods Using linked Swedish national registries, we conducted a matched cohort study of individuals ≥65 years with dementia diagnosed between 2014 and 2018, matched 1:3 to controls by age and sex, and followed until December 2019. Poisonings were identified via International Classification of Disease-10 codes. Incidence rates (IR) and hazard ratios (HR) were estimated using survival models. Results Among 415 016 participants, dementia was associated with higher poisoning incidence (IR 100.3 vs 76.4 per 100 000 person-months; HR at 6 months 1.48). Risks were greatest for unintentional poisonings, toxic pharmaceutical effects and adverse drug reactions within 6 months postdiagnosis. Psychotropics, antithrombotics and cardiovascular medications were the most commonly used. Discussion Dementia is associated with poisoning risk, warranting cautious prescribing and prevention strategies. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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