Ultra-High Frequency Ultrasound (UHFUS) Features of Pyoderma Gangrenosum, Venous Leg Ulcers, and Acute Ulcerative Lesions.
Pyoderma gangrenosum (PG) is a neutrophilic dermatological disorder, marked by the dysregulation of both innate and adaptive immunity. Recently, non-invasive imaging techniques, including the use of Ultra-High Frequency Ultrasound (UHFUS), have been used to assess patients with PG. The primary objec...
| Publicado en: | International Journal of Lower Extremity Wounds Vol. 25; no. 3; pp. 997 - 1007 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Sep2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=195893383&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 195893383 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15347346 IYG jtl: International Journal of Lower Extremity Wounds issn: 15347346 maglogo: Y pubinfo: dt: Sep2026 vid: 25 iid: 3 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 195893383 183398926 195893383 195893383 10.1177/15347346251324503 195893383 ppf: 997 ppct: 10 formats: tig: atl: Ultra-High Frequency Ultrasound (UHFUS) Features of Pyoderma Gangrenosum, Venous Leg Ulcers, and Acute Ulcerative Lesions. aug: au: Granieri, Giammarco Michelucci, Alessandra Cei, Bianca Janowska, Agata Morganti, Riccardo Romanelli, Marco Dini, Valentina affil: Department of Dermatology, University of Pisa, Pisa, Italy sug: subj: Pyoderma Gangrenosum Ultrasonography Venous Ulcer Ultrasonography Skin Ulcer Ultrasonography Ultrasonography Methods Human Italy Nonexperimental Studies Comparative Studies Chi Square Test Descriptive Statistics Data Analysis Software Wound Healing Biological Markers Pain Measurement Wound Measurement ab: Pyoderma gangrenosum (PG) is a neutrophilic dermatological disorder, marked by the dysregulation of both innate and adaptive immunity. Recently, non-invasive imaging techniques, including the use of Ultra-High Frequency Ultrasound (UHFUS), have been used to assess patients with PG. The primary objective of this study is to characterize the UHFUS differences among various cutaneous ulcerative diseases. We enrolled 45 patients: 15 patients suffered from PG (Group 1), distinguished in inflammatory phase (PG-i) and non-inflammatory phase (PG-ni); 15 patients had Venous Leg Ulcers (VLU) (Group 2); and 15 patients had Acute Injury (AI) (Group 3). For each lesion, UHFUS examination was performed with a 70 MHz linear probe to examine the angle of ulceration, epidermal and dermal morphological characteristics vascular morphology and the "scattering" signal. The study identified significant differences in the ulceration angle among various ulcerative pathologies: obtuse in Group 2, flat or straight in Group 3, predominantly acute or straight in Group 1. Moreover, PG-i phase exhibited significant fragmentation of the dermoepidermal junction (DEJ). The presence of a Subepidermal Low Echogenic Band (SLEB), hypoechogenicity of the dermis, and fluid collections were predominantly observed in the PG-i. The predominant vascular morphology in Groups 2 and 3 was regular, while in Groups 1 was irregular, presenting a high degree of "scattering" signals. The study highlights the usefulness of UHFUS as an imaging tool for assessing skin ulcers, especially those related to PG. This approach could be promising for improving diagnosis and treatment. However, further research is needed for standardization and clinical implementation. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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