Recruitment Inference Creep: Why AI in Clinical Trials Needs Auditable Ethical Limits.

The article focuses on the ethical considerations of artificial intelligence (AI)-enabled recruitment in clinical research, emphasizing the distinction between AI systems that identify eligible participants and those that optimize the likelihood of participant enrollment. While AI can improve recrui...

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Publicado en:American Journal of Bioethics Vol. 26; no. 8; pp. 70 - 72
Autores principales: Ruiz-Vanoye, Jorge A., Díaz-Parra, Ocotlán, Aguilar-Ortiz, Jaime, Ruiz-Jaimes, Miguel A., Toledo-Navarro, Yadira, Fuentes-Penna, Alejandro, Barrera-Cámara, Ricardo A., Trejo-Macotela, Francisco Rafael
Formato: Journal Article
Publicado: Taylor & Francis Ltd Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Recruitment Inference Creep: Why AI in Clinical Trials Needs Auditable Ethical Limits.
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          Ruiz-Vanoye, Jorge A.
          Díaz-Parra, Ocotlán
          Aguilar-Ortiz, Jaime
          Ruiz-Jaimes, Miguel A.
          Toledo-Navarro, Yadira
          Fuentes-Penna, Alejandro
          Barrera-Cámara, Ricardo A.
          Trejo-Macotela, Francisco Rafael
        affil: Universidad Politécnica de Pachuca
      sug:
        subj:
          Artificial Intelligence Utilization
          Research Subject Recruitment Ethical Issues
          Clinical Trials
          Discrimination
          Privacy and Confidentiality
          Consent
          Socioeconomic Factors
          Health Literacy
          Emotions
      ab: The article focuses on the ethical considerations of artificial intelligence (AI)-enabled recruitment in clinical research, emphasizing the distinction between AI systems that identify eligible participants and those that optimize the likelihood of participant enrollment. While AI can improve recruitment efficiency and accuracy, ethical concerns arise when AI shifts from eligibility detection to behavioral persuasion, potentially exploiting vulnerabilities before informed consent is obtained. The authors highlight the concept of "recruitment inference creep," where AI infers sensitive psychological or social traits to influence participation decisions, raising risks to deliberative autonomy. They advocate for institutional review boards (IRBs) to govern not only data access but also the scope of AI inferences and persuasive strategies, ensuring recruitment respects voluntary participation without manipulating prospective participants.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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