Psychotic depression with suicidality in the context of internet gaming disorder and chronic cannabis use.

A man in his 20s was admitted after a serious suicide attempt (hypnotic overdose) following months of severe depression and social withdrawal. In the preceding 2weeks, after a 2-day forced break from gaming due to a brief, mild, self-limited illness during which COVID-19 testing was not performed an...

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Bibliographic Details
Published in:BMJ Case Reports Vol. 19; no. 7; pp. 1 - 7
Main Authors: Ružić, Mirela Ćelić, Gajšak, Linda Rossini, Svetinović, Darjan, Florijan, Marijana Knezović
Format: Journal Article
Published: BMJ Publishing Group Jul2026
Online Access:View this record in EBSCOhost
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        10.1136/bcr-2026-272917
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        atl: Psychotic depression with suicidality in the context of internet gaming disorder and chronic cannabis use.
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          Ružić, Mirela Ćelić
          Gajšak, Linda Rossini
          Svetinović, Darjan
          Florijan, Marijana Knezović
        affil: Jankomir Psychiatric Hospital, Zagreb, City of Zagreb, Croatia.
      sug:
      ab: A man in his 20s was admitted after a serious suicide attempt (hypnotic overdose) following months of severe depression and social withdrawal. In the preceding 2weeks, after a 2-day forced break from gaming due to a brief, mild, self-limited illness during which COVID-19 testing was not performed and loss of in-game status, he developed derealisation and paranoid ideas that others were' non-playable characters'. His history revealed compulsive online gaming (approximately 10 hours/ day) and chronic cannabis use, and urine toxicology was positive for cannabis. He was treated with antipsychotics and antidepressants, a short course of benzodiazepines, psychoeducation and family work, with plans for cannabis abstinence and gaming restriction. Psychotic symptoms and suicidality remitted over 4weeks. At follow-up, up to 3months, clinical stability was maintained, urine toxicology was negative for cannabis and symptom measures improved. This case illustrates a clinically important temporal and phenomenological association between severe depression, problematic gaming, cannabis use and psychotic decompensation while emphasising that causality cannot be inferred from a single case.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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