Motor cortical excitability is differentially modulated by HIIT and strength exercise.

High-intensity interval training (HIIT) and strength exercise (SE) induce corticospinal plasticity in exercised and non-exercised muscles. While HIIT's systemic neuromodulatory effects are well-established, SE's comparable remote responses remain unclear. This study investigated changes in corticosp...

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Publicado en:Journal of Sports Sciences Vol. 44; no. 15; pp. 1949 - 1964
Autores principales: Rostami, Mohamad, Lee, Annemarie, Frazer, Ashlyn K., Akalu, Yonas, Siddique, Ummatul, Walker, Simon, Tallent, Jamie, Kidgell, Dawson J.
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Taylor & Francis Ltd Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2026
      vid: 44
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/02640414.2026.2705072
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        atl: Motor cortical excitability is differentially modulated by HIIT and strength exercise.
      aug:
        au:
          Rostami, Mohamad
          Lee, Annemarie
          Frazer, Ashlyn K.
          Akalu, Yonas
          Siddique, Ummatul
          Walker, Simon
          Tallent, Jamie
          Kidgell, Dawson J.
        affil: Monash Exercise Neuroplasticity Research Unit, Department of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, Australia
      sug:
        subj:
          High-Intensity Interval Training
          Cycling
          Resistance Training
          Plantarflexion
          Training Effect (Physiology)
          Motor Neurons Physiology
          Spinal Cord Physiology
          Neuronal Plasticity Evaluation
          Muscle, Skeletal
          Forearm
          Human
          Victoria
          Funding Source
          Adult
          Male
          Female
          Randomized Controlled Trials
          Random Assignment
          Crossover Design
          Transcranial Magnetic Stimulation
          Peripheral Nerves
          Electric Stimulation
          Reaction Time
          Task Performance and Analysis
          Evoked Potentials, Motor
          Questionnaires
          Neurophysiology
          Adult: 19-44 years
          Male
          Female
      ab: High-intensity interval training (HIIT) and strength exercise (SE) induce corticospinal plasticity in exercised and non-exercised muscles. While HIIT's systemic neuromodulatory effects are well-established, SE's comparable remote responses remain unclear. This study investigated changes in corticospinal, intracortical, and spinal excitability, as well as motor performance, in non-exercised flexor carpi radialis following single-session HIIT and plantar flexion SE. Using a randomised crossover design, eighteen participants completed: (1) 20-minute high-intensity interval cycling, (2) high-intensity resistive plantar flexion, and (3) control. Corticospinal responses were assessed using transcranial magnetic stimulation and peripheral nerve stimulation; motor performance through reaction time tasks and maximum voluntary force at baseline and post-exercise. Only HIIT significantly increased motor-evoked potential amplitude (p = 0.002) and reduced short-interval intracortical inhibition (p = 0.04). HIIT reduced silent period duration compared to baseline and control (p <0.001), while SE showed reduction only versus control (p <0.001). Both HIIT and SE improved reaction time compared to baseline and control (p <0.05). These findings highlight differential corticospinal responses in a remote, non-exercised muscle, with HIIT inducing distributed excitability enhancements compared to SE. Unilateral, small-muscle SE may be insufficient to induce widespread corticospinal excitability changes, with implications for neurorehabilitation strategies targeting remote muscle groups.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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