SSDA_AOA: Stacked Sparse Denoising Autoencoder With Archimedes Optimization Algorithm Based Oral Cancer Detection on Histopathological Images.

Objectives: This study aims to address the challenges in the diagnosis of oral cancer by proposing a novel computer‐aided diagnostic framework that leverages advanced deep learning (DL) and optimization techniques to enhance early detection and improve patient outcomes. Materials and Methods: In the...

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Publicado en:Oral Diseases Vol. 32; no. 6; pp. 1556 - 1571
Autores principales: Sathish Kumar, R., Govindarajan, M.
Formato: algorithm equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
      vid: 32
      iid: 6
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        196087810
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        196087810
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        10.1111/odi.70210
        196087810
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        atl: SSDA_AOA: Stacked Sparse Denoising Autoencoder With Archimedes Optimization Algorithm Based Oral Cancer Detection on Histopathological Images.
      aug:
        au:
          Sathish Kumar, R.
          Govindarajan, M.
        affil: Department of Computer Science and Engineering, Annamalai University, Chidambaram Tamil Nadu, , India
      sug:
        subj:
          Conceptual Framework
          Algorithms
          Autoencoder
          Mouth Neoplasms Diagnosis
          Mouth Neoplasms Pathology
          Diagnosis, Computer Assisted
          Early Detection of Cancer
          Deep Learning
          Early Intervention
          Image Processing, Computer Assisted
          Treatment Outcomes
          Human
          Cancer Patients
          Descriptive Statistics
          Sensitivity and Specificity
          Artificial Intelligence
          Neural Networks (Computer)
          Cancer Screening
          Machine Learning Algorithms
          Mouth Neoplasms Classification
          Image Enhancement
      ab: Objectives: This study aims to address the challenges in the diagnosis of oral cancer by proposing a novel computer‐aided diagnostic framework that leverages advanced deep learning (DL) and optimization techniques to enhance early detection and improve patient outcomes. Materials and Methods: In the framework proposed, the histopathological images are subjected to a preprocessing technique, and then, the images are fed directly to the NASNet‐Large model for the extraction of high‐level discriminative texture features. The resultant vectors obtained from the features extracted act as input to the search space of Archimedes Optimization Algorithm that carries out dimensionality reduction and optimal hyperparameter tuning simultaneously. The optimized feature subset is fed to the final classifier, namely the Stacked Sparse Denoising Autoencoder that learns robust latent representations. Results: The findings demonstrate that the proposed approach achieves superior performance, achieving an accuracy of 95.38%, a precision of 95.15%, a sensitivity of 91.78%, a specificity of 91.85%, and an F1‐score of 93.72%. Conclusions: These findings underscore the potential of the SSDA‐AOA framework as an effective tool for the early detection and precise classification of oral cancer, paving the way for improved patient outcomes through timely intervention. Clinical Relevance: This innovative approach may significantly enhance patient outcomes by facilitating earlier diagnosis and treatment, addressing the urgent need for more reliable diagnostic tools in oncology.
      pubtype: Academic Journal
      doctype:
        algorithm
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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