Evaluating Minority Representation in the All of Us Research Program: Progress and Ongoing Challenges.
Objectives. To evaluate trends in racial and ethnic representation in the All of Us (AoU) Research Program from 2017 to 2023 and assess regional disparities relative to US Census benchmarks. Methods. Using the AoU data repository, we compared yearly and cumulative racial/ethnic representation with 2...
| Publicado en: | American Journal of Public Health Vol. 116; no. 9; pp. 1339 - 1343 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | Artículo |
| Publicado: |
American Public Health Association
Sep2026
|
| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=196115367&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 196115367 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00900036 APH jtl: American Journal of Public Health issn: 00900036 maglogo: N pubinfo: dt: Sep2026 vid: 116 iid: 9 pid: 44 pub: American Public Health Association artinfo: ui: 196115367 10.2105/AJPH.2026.308441 ppf: 1339 ppct: 4 formats: tig: atl: Evaluating Minority Representation in the All of Us Research Program: Progress and Ongoing Challenges. aug: au: Qian, Zhiyu Cho, Mansoo Iyer, Hari S. Lipsitz, Stuart R. Cole, Alexander P. Kensler, Kevin Trinh, Quoc-Dien su: United States National Institutes of Health (U.S.) Medical care research African Americans Asian Americans Human research subjects Census Sex distribution Hispanic Americans Population geography White people Race Multiracial people Minorities Assigned gender Patient selection Databases Medical information storage & retrieval systems Research funding Benchmarking (Management) Descriptive statistics Odds ratio Comparative studies Confidence intervals Individualized medicine Time sug: subj: Medical care research African Americans Asian Americans Human research subjects Census Sex distribution Hispanic Americans Population geography White people Race Multiracial people Minorities Assigned gender United States National Institutes of Health (U.S.) Patient selection Databases Medical information storage & retrieval systems Research funding Benchmarking (Management) Descriptive statistics Odds ratio Comparative studies Confidence intervals Individualized medicine Time ab: Objectives. To evaluate trends in racial and ethnic representation in the All of Us (AoU) Research Program from 2017 to 2023 and assess regional disparities relative to US Census benchmarks. Methods. Using the AoU data repository, we compared yearly and cumulative racial/ethnic representation with 2020 US Census data. Odds ratios (ORs) were calculated to quantify underrepresentation by group, year, region, and sex at birth. Results. Non-Hispanic White individuals accounted for the largest percentage of the 619 830 participants (56.3%), followed by non-Hispanic Blacks (15.9%), Hispanics (14.9%), Asians (3.5%), and individuals in the multiracial/other category (9.4%). Asians and Hispanics were consistently underrepresented. Regional disparities were notable: Asian representation was lowest in the West (OR = 0.48; 95% confidence interval [CI] = 0.47, 0.49), and Hispanic underrepresentation was most pronounced in the South (OR = 0.54; 95% CI = 0.53, 0.55). Conclusions. Persistent underrepresentation of Asian and Hispanic participants highlights ongoing gaps as AoU recruitment continues. Continued efforts toward equitable participation will be important for achieving the scientific and ethical goals of precision medicine. (Am J Public Health. 2026;116(9): 1339–1342. https://doi.org/10.2105/AJPH.2026.308441) pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
|---|