Comparison of Unplanned Extubations Associated with Orotracheal versus Nasotracheal Intubation in Infants.

Abstarcts: Objective: To evaluate the association between orotracheal versus nasotracheal intubation route and unplanned extubation (UE) risk among infants. Study design: This retrospective cohort study included all tracheal intubation (TI) events among infants admitted to a level IV NICU from 2022...

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Publicado en:Journal of Perinatology Vol. 46; no. 8; pp. 1528 - 1535
Autores principales: Chitamanni, Pavani, Hays, Thomas, Vargas, Diana, Patterson, Takeya, Lush, Gloria, Lyford, Alex, Sahni, Rakesh, Kim, Faith
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2026
      vid: 46
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      pub: Springer Nature
      place: Dordrecht, <Blank>
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        10.1038/s41372-026-02615-y
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        atl: Comparison of Unplanned Extubations Associated with Orotracheal versus Nasotracheal Intubation in Infants.
      aug:
        au:
          Chitamanni, Pavani
          Hays, Thomas
          Vargas, Diana
          Patterson, Takeya
          Lush, Gloria
          Lyford, Alex
          Sahni, Rakesh
          Kim, Faith
        affil: https://ror.org/01esghr10 Division of Neonatology, Department of Pediatrics, Columbia University Irving Medical Center, 10032, New York, NY, USA
      sug:
        subj:
          Intubation, Intratracheal Methods
          Extubation, Traumatic Risk Factors
          Risk Assessment
          Infant, Hospitalized
          Intensive Care Units, Neonatal
          New York
          Human
          Infant
          Male
          Female
          Descriptive Statistics
          Inpatients
          Retrospective Design
          Record Review
          Prospective Studies
          Kaplan-Meier Estimator
          Infant: 1-23 months
          Male
          Female
      ab: Abstarcts: Objective: To evaluate the association between orotracheal versus nasotracheal intubation route and unplanned extubation (UE) risk among infants. Study design: This retrospective cohort study included all tracheal intubation (TI) events among infants admitted to a level IV NICU from 2022 to 2024. Kaplan-Meier survival analysis was used to assess UE risk by TI route. Result: There were 1160 TI events and 23 UEs during the study period. The UE rate was three times lower in the nasotracheal intubation group compared to orotracheal (0.01 vs. 0.03 per 100 ventilator days). UE risk was significantly higher in orotracheally intubated infants (p = 0.03) with no differences when stratified by sex, gestational age, or birth weight. Conclusion: Nasotracheal intubation was associated with lower UE risk in infants in a unit that predominantly performs nasotracheal intubation. Prospective randomized studies are needed to further investigate if TI route may contribute to fewer UEs in this population.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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