Ileal Perforation Caused by Pleural Mesothelioma-related Small Intestinal Involvement: A Case Report and Literature Review.
Pleural mesothelioma (PM) usually manifests as local intrathoracic invasion, and small intestinal involvement is rare. A 37-year-old man with initially diagnosed stage IV diffuse PM and no definite history of asbestos exposure or other specific occupational or environmental exposure except for long-...
| Publicado en: | Chinese Journal of Lung Cancer Vol. 29; no. 6; pp. 462 - 469 |
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| Autores principales: | , , , , , , , , , |
| Formato: | case study diagnostic images pictorial tables/charts Journal Article |
| Publicado: |
Chinese Journal of Lung Cancer
Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196270132&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196270132 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10093419 9014 jtl: Chinese Journal of Lung Cancer issn: 10093419 maglogo: N pubinfo: dt: Jun2026 vid: 29 iid: 6 pid: 54191 pub: Chinese Journal of Lung Cancer artinfo: ui: 196270132 196270132 196270132 10.3779/j.issn.1009-3419.2026.106.16 196270132 ppf: 462 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Ileal Perforation Caused by Pleural Mesothelioma-related Small Intestinal Involvement: A Case Report and Literature Review. aug: au: WANG, Yunjia SHEN, Fangqian LI, Qisha LI, Xinjuan YANG, Hua LIU, Puyu YANG, Xuefeng ZHANG, Nianjie ZHOU, Jianguo BAI, Yuju affil: Department of Thoracic Oncology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China sug: subj: Intestinal Perforation Etiology Pleural Neoplasms Complications Mesothelioma, Malignant Complications Intestine, Small Neoplasm Metastasis Intestinal Perforation Surgery Adult Male Pemetrexed Carboplatin Bevacizumab Rare Diseases Adult: 19-44 years Male ab: Pleural mesothelioma (PM) usually manifests as local intrathoracic invasion, and small intestinal involvement is rare. A 37-year-old man with initially diagnosed stage IV diffuse PM and no definite history of asbestos exposure or other specific occupational or environmental exposure except for long-term smoking was reported. After first-line treatment with Pemetrexed, Carboplatin and Bevacizumab, the disease remained stable. However, acute abdomen occurred during maintenance therapy, and emergency surgery confirmed terminal ileal perforation. Postoperative pathology suggested PM-related ileal involvement/metastatic involvement, with a higher Ki-67 proliferation index than that of the primary lesion. Because only perforation repair rather than segmental bowel resection was performed, the available pathological material could not determine whether full-thickness bowel-wall involvement was present or the direction of tumor invasion. Imaging findings, intraoperative findings and pathological results did not support primary peritoneal mesothelioma or direct contiguous invasion of the ileum by the diaphragmatic lesion; however, microscopic peritoneal dissemination with secondary bowel-wall involvement could not be completely excluded. The aim of this report, together with literature review, is to summarize the diagnostic challenges, management strategies and clinical implications of PM-related small intestinal involvement. pubtype: Academic Journal doctype: case study diagnostic images pictorial tables/charts Journal Article ougenre: Article language: Chinese refInfo: holdings: @attributes: islocal: N |
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