Enhanced Gait Variability Index in Neurological and Geriatric Rehabilitation: A Scoping Review.

Background: Gait variability is a sensitive marker of neuromotor function and a clinically relevant indicator of fall risk and mobility impairment in neurological and geriatric populations. The Enhanced Gait Variability Index (eGVI) has emerged as a promising composite measure that captures multidim...

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Publicado en:NeuroRehabilitation Vol. 59; no. 2; pp. 200 - 218
Autores principales: Wang, Mengdi, Karakkattil, Priya
Formato: review tables/charts Journal Article
Publicado: Sage Publications Inc. Sep2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2026
      vid: 59
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Enhanced Gait Variability Index in Neurological and Geriatric Rehabilitation: A Scoping Review.
      aug:
        au:
          Wang, Mengdi
          Karakkattil, Priya
        affil: School of Physical Therapy, Texas Woman's University, Dallas, TX, USA
      sug:
        subj:
          Gait Disorders, Neurologic Rehabilitation
          Gait Physiology
          Rehabilitation, Geriatric Methods
          Individualized Medicine
          Gait Analysis
          Parkinson Disease Rehabilitation
          Nervous System Diseases
          Balance, Postural Physiology
          Aging Physiology
          Walking
          Task Performance and Analysis
          Scoping Review
      ab: Background: Gait variability is a sensitive marker of neuromotor function and a clinically relevant indicator of fall risk and mobility impairment in neurological and geriatric populations. The Enhanced Gait Variability Index (eGVI) has emerged as a promising composite measure that captures multidimensional gait irregularity in a single interpretable score, offering a practical advantage over single-parameter approaches. Despite growing clinical interest, the evidence base supporting its standardized implementation has not been mapped. Objectives: To characterize populations and clinical contexts where the eGVI has been applied, map assessment protocol heterogeneity, and identify methodological gaps limiting precision medicine-aligned implementation in neurological and geriatric rehabilitation. Methods: A scoping review following PRISMA-ScR guidelines was conducted using PubMed, CINAHL, Scopus, Emcare, and Web of Science. Peer-reviewed studies reporting eGVI outcomes were included. Data were extracted on participant characteristics, gait assessment protocols, and outcomes, with attention to factors influencing clinical interpretation. Results: Eighteen studies involving 1,915 participants were included, predominantly examining Parkinson's disease (39%) and older adult populations (22%). The eGVI demonstrated preliminary sensitivity to neuromotor impairment, age-related gait changes, and increased task complexity during dual-task walking; findings were most consistent in Parkinson's disease, based on limited number of studies (n = 7). Substantial heterogeneity in walkway systems, walking conditions, assistive device use, and reference populations limited comparability. Conclusion: While the eGVI shows promise as a clinical outcome measure, protocol variability and reliance on a single unvalidated normative reference limit its clinical use. Population-specific protocols and normative data consistent with a precision medicine approach, are essential for reliable adoption.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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