| Sumario: | Background and Objectives: Cardiopulmonary resuscitation (CPR) is one of the most crucial life-saving measures for medical staff facing ethical challenges. Nurses are pioneers in the field of CPR care and treatment operations. This study aimed to explain the ethical challenges faced by nurses caring for patients undergoing CPR. Methods: This qualitative research was conducted using a phenomenological approach, with purposeful sampling and data saturation, with 12 nurses who met the criteria for participation. Data were collected using semi-structured interviews and analyzed using content analysis. Results: The mean age of the participants was 34.91, and seven were men, and five were women. Content analysis led to the discovery of four main themes and ten subcategories: 1) religious and cultural dimensions, 2) patient and family dimensions, 3) personal and human dimensions, and 4) scientific dimensions, team therapy, and regulations. Conclusion: The principle of not harming a patient with no hope of survival can be emphasized as an ethical principle by relevant authorities. Additionally, paying attention to nurses' emotions and ethical conflicts can be effective in reducing burnout.
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